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1.3.8.5: short-chain 2-methylacyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about short-chain 2-methylacyl-CoA dehydrogenase, go to the full flat file.

Word Map on EC 1.3.8.5

Reaction

2-methylbutanoyl-CoA
+
electron-transfer flavoprotein
=
(E)-2-methylbut-2-enoyl-CoA
+
reduced electron-transfer flavoprotein
+
H+

Synonyms

2-methyl branched chain acyl-CoA dehydrogenase, 2-Methyl branched-chain acyl-CoA dehydrogenase, 2-Methyl branched-chain enoyl CoA reductase, 2-Methyl branched-chain enoyl-CoA reductase, 2-methylbutyryl-CoA dehydrogenase, 2MBCD, branched chain acyl-CoA dehydrogenase, EC 1.3.99.12, ECR, Methyl branched-chain enoyl-CoA reductase, Reductase, methyl branched-chain enoyl coenzyme A, SBCAD, SBCADD, short/branched chain acyl-CoA dehydrogenase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.5 short-chain 2-methylacyl-CoA dehydrogenase

Inhibitors

Inhibitors on EC 1.3.8.5 - short-chain 2-methylacyl-CoA dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(E)-2-methyl-2-butenoyl-CoA
-
(methylenecyclopropyl)acetyl-CoA
-
0.0025 mM, slow inhibition, half-time approx. 30 min
2-butenoyl-CoA
-
0.1 mM, 53% inhibition
acetoacetyl-CoA
-
butyryl-CoA
-
0.1 mM, 50% inhibition
crotonyl-CoA
-
decanoyl-CoA
-
hexanoyl-CoA
Methylmercury iodide
N-ethylmaleimide
NEM
little effect
p-hydroxymercuribenzoate
pentanoyl-CoA
-
0.1 mM, 50% inhibition
tiglyl-CoA