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1.3.5.1: succinate dehydrogenase

This is an abbreviated version!
For detailed information about succinate dehydrogenase, go to the full flat file.

Word Map on EC 1.3.5.1

Reaction

succinate
+
a quinone
=
fumarate
 +
a quinol

Synonyms

8-methylmenaquinol:fumarate reductase, AaSdhB, bacterial succinate:quinone oxidoreductase flavoprotein, complex II, Complex II homolog, complex II of the respiratory chain, complex II succinate:ubiquinone oxidoreductase, DCPIP oxidoreductase, dehydrogenase, succinate, dehydrogenase/complex II, EC 1.3.5.4, EC 1.3.99.1, Fcc3, fdrB, FL cyt, Flavocytochrome c3, FRD, FrdA, FRdABCD, FrdC, FRdCAB, FrdD, fumarate reductase, fumarate reductase complex, fumaric hydrogenase, Ifc3, Iron(III)-induced flavocytochrome C3, iron-sulfur subunit of succinate dehydrogenase, menaquinol-1 fumarate reductase, menaquinol-fumarate oxidoreductase, menaquinol:fumarate oxidoreductase, methylmenaquinol:fumarate reductase, MFR, MFR complex, MfrA, MfrB, mitochondrial complex II, mitochondrial succinate dehydrogenase, mitochondrial succinate:ubiquinone oxidoreductase, More, mQFR, MSMEG_0416, MSMEG_0417, MSMEG_0418, MSMEG_0419, MSMEG_0420, MSMEG_1669, MSMEG_1670, MSMEG_1671, MSMEG_1672, non-classical succinate:quinone reductase, QFR, quinol-fumarate reductase, quinol:fumarate reductase, SDG, SDG-1, SDG-2, SDH, SDH1, SDH2, SDH2-1, SDH2-2, SDH3, SDH4, SdhA, sdhABE, SDHB, SdhC, sdhCAB, SdhCDAB, SdhD, SDISP, SQR, succinate dehydrogenase, succinate dehydrogenase (caldariellaquinone), succinate dehydrogenase (quinone), succinate dehydrogenase B, succinate dehydrogenase complex, succinate dehydrogenase flavoprotein subunit Sdh1p, succinate dehydrogenase iron-sulfur protein, succinate dehydrogenase iron-sulphur protein, succinate dehydrogenase subunit B, succinate oxidoreductase, succinate-2,6-dichlorophenolindophenol oxidoreductase, succinate-coenzyme Q reductase, succinate-quinone oxidoreductase, succinate-quinone reductase, succinate-ubiquinone oxidoreductase, succinate:caldariellaquinone oxidoreductase, succinate:menaquinone 7-reductase, succinate:menaquinone oxidoreductase, succinate:menaquinone reductase, succinate:MK reductase, succinate:quinone oxidoreductase, succinate:quinone reductase, succinate:quinone reductases, succinate:ubiquinone oxidoreductase, succinate:ubiquinone reductase, succinic acid dehydrogenase, succinic dehydrogenase, succinodehydrogenase, succinyl dehydrogenase, Tneu_0423

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.5 With a quinone or related compound as acceptor
                1.3.5.1 succinate dehydrogenase

Cloned

Cloned on EC 1.3.5.1 - succinate dehydrogenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
bovine cDNA for the CII-3 subunit of complex II cloned into pUC118, cloning of complete cDNA using sequence information from the bovine clone, mapping of the succinate dehydrogenase C gene
-
cDNA encoding succinate dehydrogenase iron-sulfur protein SDISP, DNA and amino acid sequence determination and analysis, expression in Escherichia coli strains M15 and Y1090
-
cDNA of iron-sulfur subunit
cell membranes transformed with plasmid which codes for all four subunits of the fumarate reductase complex
-
cloning of 2 distinct cDNAs of flavoprotein subunit of SQR
-
cloning of a mutant fumarate reductase operon
-
cloning of the complete cDNAs for the iron-sulfur protein of complex II
-
cloning of the complete cDNAs for the iron-sulfur protein of complex II from anaerobic adult
-
cloning of the fumarate reductase operon
-
cloning of the succinate dehydrogenase CDAB operon from KTA4 mutant on plasmid in Escherichia coli
-
complementation of a commercially available SDH3/SDH4 double knockout mutant yeast strain, subcloning of SDH genes in Escherichia coli strain DH5alpha
-
description of succinate dehydrogenase operon
DNA and amino acid sequence determination of mutated genes SDHB and SDHD from a Chinese family with the familial paraganglioma syndrome, pedigree of the family, overview
-
DNA and amino acid sequence determinatis of wild-type and germline mutants of the genes coding for the enzyme subunits SDHB, SDHC, and SDHD
-
expressed in Escherichia coli K12 strain
-
expressed in Escherichia coli strain DW35
-
expressed in Mortierella alpina 1S-4
expression in Escherichia coli
expression of HA-tagged Sdh1p coupled to the Escherichia coli lacZ reporter gene
-
expression of subunit SdhE (formerly SdhC) in Escherichia coli
Q97W79; Q97W78; Q97W77; Q97W76
expression of wild-type and mutant enzymes in strain DW35
-
gene cluster frdABCD encoding 4 subunits, DNA and amino acid sequence analysis, overepression
gene cluster sdhCDAB encoding 4 subunits, DNA and amino acid sequence analysis, overepression
gene MSMEG_1671, recombinant expression of C-terminally His10-tagged protein Sdh2D in Mycobacterium smegmatis mutant strain mc2 51
A0QT08; A0QT07; A0QT10; A0QT09
gene sdh2, disruption of the SDH2 gene and transformation into the sdh1 mutant strain, resulting in SDH-negative strain B2S
-
gene SDH2-2, expression analysis, antisense expressionin transgenic Solanum lycopersicumplants by Agrobacterium tumefaciens-mediated transformation
gene sdhA from Escherichia coli strain MC4100, recombinant expression of non-tagged SdhA in Escherichia coli strain BL21(DE3) CodonPlus-RIL, coexpression with His6-tagged SdhE
gene SDHB ecoding the subunit B, genotype-phenotype correlations among patients with SDHB mutations in different exons do not reveal obvious differences for age at presentation, biochemical phenotype, primary tumor size and location, distribution of metastatic lesions, or presence of additional head and neck paragangliomas, overview
-
gene SDHB, chromoslomal location at 1p36.13, DNA and amino acid sequence determination and analysis of wild-type and mutant enzymes
-
gene sdhB, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis
gene SDHD, DNA and amino acid sequence determination and analysis of wild-type and mutant genes
-
gene SDHD, encoding the cybS subunit of the succinate dehydrogenase, mapps to chromosome 11q23, genotyping of native wild-type and mutant genes, overview
-
genes encoding subunits SdhC, SdhD, and SdhB are located at 1q21,11q23, and 1p35-36.1
-
genes SDHA, SDHB, SDHC, and SDHD
-
genes SDHB, SDHC, and SDHD, DNA and amino acid sequence determination and analysis, genotyping
-
genes sdhC and sdhD, DNA and amino acid sequence determination and analysis, the genes form an operon with the pep1 gene, genetic organization, transcriptional mapping, sdh gene phylogenetic analysis, overview
-
genes SDHC, SDHD, and SDHB, DNA and amino acid sequence determination and analysis, expression analysis in healthy individuals and in patients with Cowden and Cowden-like syndromes, the latter show PTEN mutations, overview
-
genes SDHD and SDHB, DNA and amino acid sequence determination of healthy individuals and patients with paraganglioma and phaeochromocytomas, several samples, overview
-
genes SDHD and SDHB, DNA and amino acid sequence determination of healthy individuals and patients with paraganglioma and phaeochromocytomas, several smaples, overview
-
operon FrdABCD, recombinant expression of wild-type and mutant FrdAs in Escherichia coli strain DW35, in which both the frd and sdh operons are disrupted via the insertion of a kanamycin gene
overview succinate dehydrogenase and fumarate reductase
-
recombinant expression of C-terminally His6-tagged or N-termminally His8-tagged enzyme in Thermus thermophilus under the control of a constitutive promoter
-
sdhB from mutant H229Y is ligated into a cosmid, pUFR034, to generate pUFR034RAX, which confers resistance to amicarthiazol when transformed into the wild-type sensitive strain
SdhC and the N-terminal domain fragment of SdhB of respiratory complex II are overproduced in Escherichia coli
F9VN10; Q9C4L8; F9VN12; F9VN13
site directed mutagenesis at substrate binding site
-
subunit B encoding gene SDHB, DNA and amino acid sequence determination, genotyping, overview
subunit C encoding gene SDHC, DNA and amino acid sequence determination, genotyping, overview
subunit encoding genes SDHA, and SDHD, DNA and amino acid sequence determination, genotyping, overview
targeted gene diruption of iron-sulfur protein
-
the encoding plasmid is transformed in Wolinella succinogenes
-
transformed strain DW35 used for expression of membrane-bound enzyme
-
two structural genes coding for subunits of the enzyme cloned in Escherichia coli, polarity and organization of the genes
-