1.3.3.8: tetrahydroberberine oxidase
This is an abbreviated version!
For detailed information about tetrahydroberberine oxidase, go to the full flat file.
Word Map on EC 1.3.3.8
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1.3.3.8
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berberis
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dehydrogenation
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s-scoulerine
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japonica
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coptis
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columbamine
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palmatine
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somniferum
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morphine
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jatrorrhizine
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isoquinoline
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compartmentation
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flavoprotein
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methylenedioxy
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papaver
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benzylisoquinoline
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s-tetrahydrocolumbamine
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s-reticuline
- 1.3.3.8
- berberis
-
dehydrogenation
-
s-scoulerine
- japonica
- coptis
- columbamine
- palmatine
- somniferum
- morphine
- jatrorrhizine
- isoquinoline
-
compartmentation
- flavoprotein
-
methylenedioxy
-
papaver
-
benzylisoquinoline
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s-tetrahydrocolumbamine
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s-reticuline
Reaction
Synonyms
(S)-H4Ber oxidase, (S)-tetrahydroberberine oxidase, (S)-THB oxidase, EC 1.5.3.8, oxidase, (S)-tetrahydroberberine, THBO
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results (Natural Substrates Products
Natural Substrates Products on EC 1.3.3.8 - tetrahydroberberine oxidase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(S)-tetrahydroberberine + 2 O2
protoberberine + 2 H2O2
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7,14-dehydroberberinium as intermediate, protoberberine biosynthesis
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?
additional information
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the recombinant enzyme expressed in transgenic Eschscholzia californica cells produces coptisine and dehydrocheilanthifoline from pathway intermediates cheilanthifoline and stylopine, overview
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?
(S)-tetrahydroberberine + 2 O2
berberine + 2 H2O2
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final step in berberine biosynthesis
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?
(S)-tetrahydroberberine + 2 O2
berberine + 2 H2O2
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?
