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1.3.3.4: protoporphyrinogen oxidase

This is an abbreviated version!
For detailed information about protoporphyrinogen oxidase, go to the full flat file.

Word Map on EC 1.3.3.4

Reaction

protoporphyrinogen IX
+ 3 O2 =
protoporphyrin IX
 + 3 H2O2

Synonyms

HemG, HemG-type PPO, HemG-type protoporphyrinogen IX oxidase, hemY, hPPO, H_N10, H_N40, H_N90, LMJF_06_1280, mtPPO, MxPPOX, MxProtox, PPO, PPO1, ppo1-1, PPO2, PPOX, PPOX I, PPX1, PPX2, protein YfeX, protogen oxidase, protoporphyrinogen IX oxidase, protoporphyrinogen IX oxidase 1, protoporphyrinogen oxidase, protoporphyrinogen oxidase IX, protoporphyrinogenase, protox, Protox enzyme, R-PPO, Rs-slr1790 protein, S-PPO, Salk_143057, YfeX

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.4 protoporphyrinogen oxidase

Activating Compound

Activating Compound on EC 1.3.3.4 - protoporphyrinogen oxidase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Diamide
-
activates the N-terminally processed-like enzyme form and processed native form
dicoumarol
-
below 0.015 mM
dithiothreitol
-
-
fatty acid
-
required for full activity
H2O2
-
activates the N-terminally processed-like enzyme form and processed native form
imidazole
activates recombinant wild-type enzyme and mutant V311M
Irgarol 1051
-
increases cnidarian PPO
-
iron-EDTA
-
in presence of glutathione
Lipids
-
-
-
n-octylglucopyranoside
-
1 mM results in maximal activity
oleic acid
Tween 20
activates recombinant wild-type enzyme and mutant V311M
Ubiquinone-10
-
below 0.015 mM
ubiquinone-6
-
below 0.015 mM