1.3.1.B13: polyprenol reductase (NADPH)
This is an abbreviated version!
For detailed information about polyprenol reductase (NADPH), go to the full flat file.
Word Map on EC 1.3.1.B13
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1.3.1.B13
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services
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violation
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reimbursement
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terminology
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bill
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lorentz
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medicare
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revisions
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sidereal
- 1.3.1.B13
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services
-
violation
-
reimbursement
-
terminology
-
bill
-
lorentz
-
medicare
-
revisions
-
sidereal
Reaction
Synonyms
polyprenol reductase, polyprenol reductase 1, polyprenol reductase 2, polyprenol reductase2, PPRD1, PPRD2, SRD5A3
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Natural Substrates Products on EC 1.3.1.B13 - polyprenol reductase (NADPH)
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REACTION DIAGRAM
a polyprenol + NADPH + H+
a dolichol + NADP+
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a polyprenol + NADPH + H+
a dolichol + NADP+
the enzyme (SRD5A3) is necessary for the reduction of the alpha-isoprene unit of polyprenols to form alpha-reduced dolichols, required for synthesis of dolichol-linked monosaccharides, and the oligosaccharide precursor used for N-glycosylation. The presence of residual dolichol in cells depleted for this enzyme suggests the existence of an unexpected alternative pathway for dolichol de novo biosynthesis
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