1.3.1.76: precorrin-2 dehydrogenase
This is an abbreviated version!
For detailed information about precorrin-2 dehydrogenase, go to the full flat file.
Word Map on EC 1.3.1.76
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1.3.1.76
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uroporphyrinogen
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sirohaem
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dehydrogenation
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ferrochelation
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sirohydrochlorin
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prosthetic
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cobalamin
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cobalt
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tetrapyrrole
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nitrite
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nad+-dependent
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megaterium
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sulfite
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sulfur
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reductases
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methylase
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transmethylase
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renamed
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typhimurium
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synthases
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s-adenosyl-l-methionine-dependent
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cobaltochelatase
- 1.3.1.76
- uroporphyrinogen
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sirohaem
-
dehydrogenation
-
ferrochelation
- sirohydrochlorin
-
prosthetic
- cobalamin
- cobalt
- tetrapyrrole
- nitrite
-
nad+-dependent
- megaterium
- sulfite
- sulfur
- reductases
-
methylase
-
transmethylase
-
renamed
- typhimurium
- synthases
-
s-adenosyl-l-methionine-dependent
- cobaltochelatase
Reaction
Synonyms
cobaltochelatase, CysG, CysG enzyme, cysG gene product, CysG2, EC 2.1.1.107, Met8p, P2D, precorrin-2 dehydrogenase, S-adenosyl-L-methionine(SAM)-dependent bismethyltransferase, dehydrogenase and ferrochelatase, SirC, siroheme synthase, siroheme synthetase
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.3.1.76 - precorrin-2 dehydrogenase
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REACTION DIAGRAM
sirohydrochlorin + Fe2+
siroheme + H+
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-
?
sirohydrochlorin + NADH + H+
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multifunctional protein involved in S-adenosyl-L-methionine-dependent methylation, pyridine dinucleotide dependent dehydrogenation, and ferrochelation, second of three steps leading to formation of siroheme from uroporphyrinogen III
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?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
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multifunctional protein involved in S-adenosyl-L-methionine-dependent methylation, pyridine dinucleotide dependent dehydrogenation, and ferrochelation, second of three steps leading to formation of siroheme from uroporphyrinogen III
-
?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
siroheme and cobalamin biosynthesis, second of three steps leading to formation of siroheme from uroporphyrinogen III
-
?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
Priestia megaterium DSM 509
siroheme and cobalamin biosynthesis, second of three steps leading to formation of siroheme from uroporphyrinogen III
-
?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
second of three steps leading to formation of siroheme from uroporphyrinogen III
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?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
bifunctional dehydrogenase and ferrochelatase, second of three steps leading to formation of siroheme from uroporphyrinogen III
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?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
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siroheme and cobalamin biosynthesis, second of three steps leading to formation of siroheme from uroporphyrinogen III
-
?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
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tetrapyrrole and cobalamin biosynthesis, second of three steps leading to formation of siroheme from uroporphyrinogen III
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?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
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-
-
?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
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precorrin-2 is the precursor of both siroheme and B12, first reaction specific to B12 synthesis, second of three steps leading to formation of siroheme from uroporphyrinogen III
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?
precorrin-2 + NAD+
sirohydrochlorin + NADH + H+
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-
-
?