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1.3.1.32: maleylacetate reductase

This is an abbreviated version!
For detailed information about maleylacetate reductase, go to the full flat file.

Word Map on EC 1.3.1.32

Reaction

3-oxoadipate
+
NAD(P)+
=
2-maleylacetate
+
NAD(P)H
+
H+

Synonyms

GraC, hadD, hqdD, HqoD, HxqD, MAA reductase, maleoylacetate reductase, maleylacetate reductase, MAR, PcpE, pdcF, PnpD, TcpD, tfdF, tsdD

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.32 maleylacetate reductase

Substrates Products

Substrates Products on EC 1.3.1.32 - maleylacetate reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,3,5-trichloromaleylacetate + NADH
2,4-dichloro-3-oxohexanedioic acid + NAD+ + Cl-
show the reaction diagram
2,3-dibromomaleylacetate + NADH
3-bromo-4-oxohexanedioic acid + NAD+ + Br-
show the reaction diagram
2,3-dichloromaleylacetate + NADH
3-chloro-4-oxohexanedioic acid + NAD+ + Cl-
show the reaction diagram
2,4-dichlorophenoxyacetate + NADH
?
show the reaction diagram
2,5-dibromomaleylacetate + NADH
5-bromo-4-oxohex-2-enedioic acid + Br- + NAD+
show the reaction diagram
-
-
-
?
2,5-dichloromaleylacetate + NADH
2-chloro-3-oxohexanedioic acid + NAD+ + Cl-
show the reaction diagram
2-bromo-5-chloromaleylacetate + NADH
5-chloro-4-oxohex-2-enedioic acid + Br- + NAD+
show the reaction diagram
-
-
-
?
2-bromomaleylacetate + NADH
2-maleylacetate + NAD+ + Br-
show the reaction diagram
2-chloro-3-methylmaleylacetate + NADH
3-methyl-4-oxohex-2-enedioic acid + NAD+ + Cl-
show the reaction diagram
-
-
the product is further reduced to 3-methyl-4-oxohexanedioic acid under consumption of NADH
?
2-chloro-5-methylmaleylacetate + NADH
5-methyl-4-oxohex-2-enedioic acid + NAD+ + Cl-
show the reaction diagram
-
-
the product is further reduced to 2-methyl-3-oxohexanedioic acid under consumption of NADH
?
2-chloromaleylacetate + NAD(P)H
? + NAD(P)+
show the reaction diagram
2-chloromaleylacetate + NADH
2-maleylacetate + Cl- + NAD+
show the reaction diagram
2-chloromaleylacetate + NADH
maleylacetate + NAD+ + Cl-
show the reaction diagram
final enzyme in the pentachlorophenol biodegradation pathway which catalyzes the reductive dehalogenation of 2-chloromaleylacetate to maleylacetate and the subsequent reduction of malyelacetate to 3-oxoadipate
-
-
?
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + Cl-
show the reaction diagram
2-chloromaleylacetate + NADH + H+
maleylacetate + NAD+ + HCl
show the reaction diagram
2-chloromaleylacetate + NADPH
2-maleylacetate + Cl- + NADP+
show the reaction diagram
2-chloromaleylacetate + NADPH + H+
maleylacetate + NADP+ + Cl-
show the reaction diagram
2-chloromaleylacetate + NADPH + H+
maleylacetate + NADP+ + HCl
show the reaction diagram
-
-
-
?
2-fluoromaleylacetate + NADH
3-oxoadipate + NAD+ + F-
show the reaction diagram
-
-
-
?
2-maleylacetate + NAD(P)H
3-oxoadipate + NAD(P)+
show the reaction diagram
2-maleylacetate + NAD(P)H + H+
3-oxoadipate + NAD(P)+
show the reaction diagram
2-maleylacetate + NADH
3-oxoadipate + NAD+
show the reaction diagram
2-maleylacetate + NADH + H+
3-oxoadipate + NAD+
show the reaction diagram
2-maleylacetate + NADPH
3-oxoadipate + NADP+
show the reaction diagram
2-maleylacetate + NADPH + H+
3-oxoadipate + NADP+
show the reaction diagram
2-methyl-3-chloromaleylacetate + NADH
3-chloro-2-methyl-4-oxohexanedioic acid + NAD+
show the reaction diagram
2-methylmaleylacetate + NAD(P)H
5-methyl-3-oxoadipate + NAD(P)+
show the reaction diagram
3-bromomaleylacetate + NADH
3-bromo-4-oxohexanedioic acid + NAD+
show the reaction diagram
3-chloromaleylacetate + NADH
3-chloro-4-oxohexanedioic acid + NAD+
show the reaction diagram
3-fluoromaleylacetate + NADH
2-fluoro-3-oxohexanedioic acid + NAD+
show the reaction diagram
-
-
-
?
3-methylmaleylacetate + NAD(P)H
4-methyl-3-oxoadipate + NAD(P)+
show the reaction diagram
5-bromomaleylacetate + NADH
2-bromo-3-oxohexanedioic acid + NAD+
show the reaction diagram
5-chloromaleylacetate + NADH
2-chloro-3-oxohexanedioic acid + NAD+
show the reaction diagram
5-fluoromaleylacetate + NADH
2-fluoro-3-oxohexanedioic acid + NAD+
show the reaction diagram
5-methylmaleylacetate + NAD(P)H
2-methyl-3-oxoadipate + NADP+
show the reaction diagram
cis,cis-3-hydroxymuconate + NADPH
? + NADP+
show the reaction diagram
maleylacetate + NADH
3-oxoadipate + NAD+
show the reaction diagram
-
-
-
?
phenoxyalacanoic herbicide 2,4,5-T + NADH
? + NAD+
show the reaction diagram
phenoxyalacanoic herbicide 2,4-D + NADH
? + NAD+
show the reaction diagram
trans,cis-3-hydroxymuconate + NADPH
? + NADP+
show the reaction diagram
additional information
?
-