1.3.1.12: prephenate dehydrogenase
This is an abbreviated version!
For detailed information about prephenate dehydrogenase, go to the full flat file.
Reaction
+
=
+
+
+
Synonyms
AceF, AroQ, bifunctional T-protein, chorismate mutase-prephenate dehydratase, chorismate mutase-prephenate dehydrogenase bifunctional enzyme, chorismate mutase-T:prephenate dehydrogenase bifunctional enzyme, Chorismate mutase/prephenate dehydratase, CM-PD, CM-TyrAp, CM/PDT/PDHG, CMPD, dehydrogenase, prephenate, hydroxyphenylpyruvate synthase, PD, PDH, pdhE-1, PDHG, T-protein, TYR1, tyrA, TyrA dehydrogenase, TyrAp
ECTree
KM Value
KM Value on EC 1.3.1.12 - prephenate dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.017 - 0.249
L-arogenate
additional information
additional information
-
Km of enzyme fragments
-
0.017
L-arogenate
-
at 30°C, wild-type
0.041
L-arogenate
-
at 30°C, delta19PD
0.097
L-arogenate
-
at 55°C, wild-type
0.135
L-arogenate
-
at 55°C, delta19PD
0.136
L-arogenate
-
at 80°C, wild-type
0.249
L-arogenate
-
at 80°C, delta19PD
0.01
NAD+
mutant H217A, pH 7.5, 55°C
0.012
NAD+
mutant H217N, pH 7.5, 55°C
0.025
NAD+
-
at 30°C, wild-type
0.053
NAD+
-
at 30°C, delta19PD
0.071
NAD+
-
at 55°C, delta19PD
0.071
NAD+
wild-type, pH 7.5, 55°C
0.072
NAD+
-
at 55°C, wild-type
0.084
NAD+
-
at 80°C, delta19PD
0.089
NAD+
mutant R250Q, pH 7.5, 55°C
0.099
NAD+
mutant S126A, pH 7.5, 55°C
0.103
NAD+
-
wild-type enzyme
0.109
NAD+
-
at 80°C, wild-type
0.128 - 0.141
NAD+
-
mutant forms H197N and K37Q
0.38
NAD+
-
mutant form R294Q
0.017
prephenate
-
at 30°C, wild-type
0.041
prephenate
-
at 30°C, delta19PD
0.045
prephenate
presence of 0.002 mM L-tyrosine, pH 7.5, 25°C
0.045 - 0.09
prephenate
-
-
0.045 - 0.09
prephenate
-
-
0.045 - 0.09
prephenate
-
-
0.045 - 0.09
prephenate
-
-
0.045 - 0.09
prephenate
-
-
0.045 - 0.09
prephenate
-
-
0.048
prephenate
-
at pH 7.2 and 30°C
0.054 - 0.055
prephenate
-
mutant forms K37Q and H197N
0.056
prephenate
presence of 0.006 mM L-tyrosine, pH 7.5, 25°C
0.057
prephenate
pH 7.5, 25°C
0.097
prephenate
-
at 55°C, wild-type
0.104
prephenate
mutant H147N, pH 7.5, 55°C
0.11
prephenate
-
presence of bovine serum albumin
0.135
prephenate
-
at 55°C, delta19PD
0.135
prephenate
wild-type, pH 7.5, 55°C
0.136
prephenate
-
at 80°C, wild-type
0.249
prephenate
-
at 80°C, delta19PD
0.25
prephenate
-
with NAD+ as cosubstrate, at pH 7.6 and 37°C
0.32
prephenate
with NAD+ as cosubstrate, at pH 7.6 and 37°C
0.35 - 0.37
prephenate
-
-
0.35 - 0.37
prephenate
-
-
0.45
prephenate
pH 6.5, 87°C
0.56
prephenate
-
cofactor NADP+
0.57
prephenate
-
cofactor NAD+
0.75
prephenate
pH 6.8, 37°C
0.87
prephenate
pH 8.0, 45°C
1.185
prephenate
mutant R250Q, pH 7.5, 55°C
1.335
prephenate
mutant S126A, pH 7.5, 55°C
3.213
prephenate
mutant H217N, pH 7.5, 55°C
4.132
prephenate
mutant H217A, pH 7.5, 55°C
5
prephenate
-
mutant form R294Q