1.3.1.110: lactate dehydrogenase (NAD+, ferredoxin)
This is an abbreviated version!
For detailed information about lactate dehydrogenase (NAD+, ferredoxin), go to the full flat file.
Word Map on EC 1.3.1.110
-
1.3.1.110
-
perfringens
-
enterotoxin
-
pastoral
-
supervisor
-
carbapenemase-producing
-
carbapenemase
-
non-food-borne
- 1.3.1.110
-
perfringens
-
enterotoxin
-
pastoral
-
supervisor
-
carbapenemase-producing
- carbapenemase
-
non-food-borne
Reaction
Synonyms
lactate dehydrogenase-EtfAB complex, LctD, LDH/Etf complex
ECTree
1.3.1.110 lactate dehydrogenase (NAD+, ferredoxin)Advanced search results
results (
results (Substrates Products
Substrates Products on EC 1.3.1.110 - lactate dehydrogenase (NAD+, ferredoxin)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
lactate + 2 NAD+ + 2 reduced ferredoxin [iron-sulfur] cluster
pyruvate + 2 NADH + 2 oxidized ferredoxin [iron-sulfur] cluster
-
-
-
-
?
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
lactate is a common substrate for major groups of strictly anaerobic bacteria. The LDH/Etf complex of Acetobacterium woodii uses flavin-based electron confurcation to drive endergonic lactate oxidation with NAD+ as oxidant at the expense of simultaneous exergonic electron flow from reduced ferredoxin to NAD+
-
-
r
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
pyruvate reduction to lactate with NADH as electron donor is highly exergonic
-
-
r
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
lactate is a common substrate for major groups of strictly anaerobic bacteria. The LDH/Etf complex of Acetobacterium woodii uses flavin-based electron confurcation to drive endergonic lactate oxidation with NAD+ as oxidant at the expense of simultaneous exergonic electron flow from reduced ferredoxin to NAD+
-
-
r
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
pyruvate reduction to lactate with NADH as electron donor is highly exergonic
-
-
r
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
no NADH oxidation with pyruvate as electron acceptor. Only when oxidized ferredoxin is added to the system, the reaction is initiated and NADH oxidation is detected by a decrease of absorbance. NADH-dependent ferredoxin reduction is strictly dependent on the presence of lactate
-
-
r
pyruvate + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster
lactate + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
no NADH oxidation with pyruvate as electron acceptor. Only when oxidized ferredoxin is added to the system, the reaction is initiated and NADH oxidation is detected by a decrease of absorbance. NADH-dependent ferredoxin reduction is strictly dependent on the presence of lactate
-
-
r
