1.3.1.105: 2-methylene-furan-3-one reductase
This is an abbreviated version!
For detailed information about 2-methylene-furan-3-one reductase, go to the full flat file.
Reaction
Synonyms
FaEO, SIEO
ECTree
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Substrates Products
Substrates Products on EC 1.3.1.105 - 2-methylene-furan-3-one reductase
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REACTION DIAGRAM
(2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADH + H+
2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NAD+
(2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADH + H+
4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NAD+
(2E)-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADH + H+
2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NAD+
(2E)-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+
2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + 5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone + NADP+
-
-
-
?
4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADH + H+
(2R)-4-hydroxy-2,5-dimethyl-3(2H)-furanone + NAD+
kcat/Km for NADH is 7.5fold lower than for NADPH, Re-specific, i.e. the 4R-hydride of NAD(P)H is transferred
-
-
?
4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADH + H+
4-hydroxy-2,5-dimethyl-3(2H)-furanone + NAD+
4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADPH + H+
(2R)-4-hydroxy-2,5-dimethyl-3(2H)-furanone + NADP+
kcat/Km for NADH is 7.5fold lower than for NADPH, Re-specific, i.e. the 4R-hydride of NAD(P)H is transferred
-
-
?
4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADPH + H+
4-hydroxy-2,5-dimethyl-3(2H)-furanone + NADP+
-
-
-
?
2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NAD+
-
-
-
?
(2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADH + H+
2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NAD+
-
-
-
-
?
4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NAD+
-
-
-
?
(2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADH + H+
4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NAD+
-
-
-
-
?
2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NAD+
-
-
-
?
(2E)-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADH + H+
2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NAD+
-
-
-
-
?
4-hydroxy-2,5-dimethyl-3(2H)-furanone + NAD+
-
-
-
?
4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADH + H+
4-hydroxy-2,5-dimethyl-3(2H)-furanone + NAD+
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-
-
-
?
?
-
no reaction with (2E)-2-hexenal, (3E)-3-hexen-2-one, (3E)-5-methyl-3-hexen-2-one, cyclohexa-1,2-dione, buta-2,3-dione, coumarin, astaxanthin, cinnamyl aldehyde, 4-coumaric acid, ferulic acid, dimethoxycinnamic acid, or benzil
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-
?
additional information
?
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no reaction with (2E)-2-hexenal, (3E)-3-hexen-2-one, (3E)-5-methyl-3-hexen-2-one, cyclohexa-1,2-dione, buta-2,3-dione, coumarin, astaxanthin, cinnamyl aldehyde, 4-coumaric acid, ferulic acid, dimethoxycinnamic acid, or benzil
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-
?