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1.21.3.1: isopenicillin-N synthase

This is an abbreviated version!
For detailed information about isopenicillin-N synthase, go to the full flat file.

Word Map on EC 1.21.3.1

Reaction

N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine
+
O2
=
isopenicillin N
+ 2 H2O

Synonyms

IPN cyclase, IPN synthase, IPNS, isopenicillin N synthase, isopenicillin N synthase (cyclase), isopenicillin N synthetase, isopenicillin N-synthase, isopenicillin-N synthase, isopenicillin-N-synthase, More, PcbC, synthetase, isopenicillin N (9Cl)

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.3 With oxygen as acceptor
                1.21.3.1 isopenicillin-N synthase

Sequence

Sequence on EC 1.21.3.1 - isopenicillin-N synthase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
IPNA_ACRCH
338
0
38433
Swiss-Prot
other Location (Reliability: 2)
IPNA_EMENI
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
331
0
37522
Swiss-Prot
other Location (Reliability: 2)
IPNA_PENCH
331
0
37960
Swiss-Prot
other Location (Reliability: 2)
IPNA_PENRW
Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)
331
0
38010
Swiss-Prot
other Location (Reliability: 2)
IPNS_AMYLA
328
0
37466
Swiss-Prot
-
IPNS_LYSLA
326
0
36564
Swiss-Prot
-
IPNS_STRCL
329
0
36959
Swiss-Prot
-
IPNS_STRCT
321
0
36577
Swiss-Prot
-
IPNS_STRGR
329
0
37368
Swiss-Prot
-
IPNS_STRJU
329
0
37305
Swiss-Prot
-
IPNS_STRMI
333
0
38082
Swiss-Prot
-
A0A0K2DZQ9_PISSA
280
0
31341
TrEMBL
-
B3R9G9_CUPTR
Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1)
332
0
37498
TrEMBL
-
A4A7I1_9GAMM
280
0
30734
TrEMBL
-
G4I7R5_MYCRH
342
0
37153
TrEMBL
-
S6CWX8_ACEPA
336
0
38277
TrEMBL
-
G7EM52_9GAMM
279
0
31169
TrEMBL
-
A0A375C5P1_9BURK
332
0
37254
TrEMBL
-
U2ENB9_9GAMM
339
0
36961
TrEMBL
-
K6XKJ2_9ALTE
279
0
31269
TrEMBL
-
A0A7W9QHN8_9XANT
326
0
36703
TrEMBL
-
A0A375CMY7_9BURK
332
0
37445
TrEMBL
-
E2Q5R0_STRCL
343
0
38432
TrEMBL
-
A0A0U0ZLS8_9MYCO
355
0
38609
TrEMBL
-
K9QKU9_9NOSO
332
0
37530
TrEMBL
-
Q1LE23_CUPMC
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
330
0
37487
TrEMBL
-
Q09B48_STIAD
Stigmatella aurantiaca (strain DW4/3-1)
349
0
37907
TrEMBL
-
K6XUT7_9ALTE
279
0
31263
TrEMBL
-
A0A375E7T9_9BURK
332
0
37415
TrEMBL
-
K6XIT9_9ALTE
279
0
31501
TrEMBL
-
W6RJX4_9HYPH
644
5
70633
TrEMBL
-
Q3M330_TRIV2
Trichormus variabilis (strain ATCC 29413 / PCC 7937)
330
0
37432
TrEMBL
-
A0A1Z3HMV8_9CYAN
309
0
34057
TrEMBL
-
B8CPR3_SHEPW
Shewanella piezotolerans (strain WP3 / JCM 13877)
279
0
31572
TrEMBL
-
H5T8D4_9ALTE
279
0
31565
TrEMBL
-
G7ESL5_9GAMM
279
0
31308
TrEMBL
-
K6Z6G5_9ALTE
279
0
31279
TrEMBL
-
D5BUA1_PUNMI
Puniceispirillum marinum (strain IMCC1322)
276
0
30879
TrEMBL
-
A0A0H5BYE7_CYBJN
Cyberlindnera jadinii (strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 / NBRC 0987 / NRRL Y-1542)
332
0
37914
TrEMBL
other Location (Reliability: 1)
Q3IIP3_PSET1
Pseudoalteromonas translucida (strain TAC 125)
279
0
31191
TrEMBL
-
V9ZXT4_AERHY
279
0
31712
TrEMBL
-
G7G811_9GAMM
279
0
31154
TrEMBL
-
A0A7Z7NP81_9BURK
332
0
37483
TrEMBL
-
A0A1Y5P3I9_9MYCO
341
0
37298
TrEMBL
-
A0A073L0M5_9GAMM
279
0
31504
TrEMBL
-
A0A7J0CA49_9ACTN
329
0
37242
TrEMBL
-
K7AF84_9ALTE
279
0
31335
TrEMBL
-
A0A7W9JZW9_9XANT
328
0
36889
TrEMBL
-
K1QF46_CRAGI
292
0
33304
TrEMBL
other Location (Reliability: 1)
K9MVH8_FOLCA
333
0
37861
TrEMBL
other Location (Reliability: 1)