1.20.4.4: arsenate reductase (thioredoxin)
This is an abbreviated version!
For detailed information about arsenate reductase (thioredoxin), go to the full flat file.
Reaction
Synonyms
ARS, ArsC, ArsC1, ArsC1', ArsC3, arsenate reductase, Bs_ArsC, pI258 arsenate reductase, plasmid pI258 arsenate reductase, Sa_ArsC, Strop634, thioredoxin-arsenate reductase complex, thioredoxin-coupled arsenate reductase, Trx-coupled arsenate reductase
ECTree
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Substrates Products
Substrates Products on EC 1.20.4.4 - arsenate reductase (thioredoxin)
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REACTION DIAGRAM
arsenite + thioredoxin disulfide + H2O
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?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
-
-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
-
-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
Oleidesulfovibrio alaskensis
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-
-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
Oleidesulfovibrio alaskensis G20
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-
-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
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-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
-
-
-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
-
-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
the enzyme encoded by Staphylococcus aureus arsenic-resistance plasmid pI258 reduces intracellular arsenate to the more toxic arsenite, which is subsequently extruded from the cell
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-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
glutaredoxin and reduced glutathione does not stimulate arsenate reduction
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-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
the enzyme uses an intramolecular thiol pair (Cys82, Cys89) for the reduction of arsenate
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-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
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-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
-
-
-
?
arsenate + thioredoxin
arsenite + thioredoxin disulfide + H2O
Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039
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?
?
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assays are performed with different arsenate concentrations and arsenate reductase concentrations in the presence of 0.42 microM Escherichia coli thioredoxin, 0.14 microM Escherichia coli thioredoxin reductase and 125 microM NADPH
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additional information
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enzyme additionally exhibits weak phosphatase activity
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?
additional information
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enzyme additionally exhibits weak phosphatase activity
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additional information
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Thermus thermophilus HB27 / ATCC BAA-163 / DSM 7039
enzyme additionally exhibits weak phosphatase activity
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?