1.20.4.4: arsenate reductase (thioredoxin)

This is an abbreviated version!
For detailed information about arsenate reductase (thioredoxin), go to the full flat file.

Reaction

Synonyms

ARS, ArsC, ArsC1, ArsC1', ArsC3, arsenate reductase, Bs_ArsC, pI258 arsenate reductase, plasmid pI258 arsenate reductase, Sa_ArsC, Strop634, thioredoxin-arsenate reductase complex, thioredoxin-coupled arsenate reductase, Trx-coupled arsenate reductase

ECTree

     1 Oxidoreductases

         1.20 Acting on phosphorus or arsenic in donors

             1.20.4 With disulfide as acceptor

                1.20.4.4 arsenate reductase (thioredoxin)

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
5	Activating Compound
1950	AA Sequence
14	Cloned(Commentary)
9	Cofactor
4	Crystallization (Commentary)
5	Expression
13	General Information
6	Inhibitors
23	kcat/KM [mM/s]
3	Ki Value [mM]
27	KM Value [mM]
1	Localization
2	Metals/Ions
21	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
22	Organism
1	Pathway
4	pH Optimum
1	pH Range
1	pH Stability
2	pI Value
34	Protein Variants
11	Purification (Commentary)
1	Reaction
18	Reference
1	Specific Activity [micromol/min/mg]
22	Substrates and Products (Substrate)
12	Subunits
37	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
27	Turnover Number [1/s]

Natural Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Natural Substrates Products on EC 1.20.4.4 - arsenate reductase (thioredoxin)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Natural Substrate Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

arsenate + thioredoxin

arsenite + thioredoxin disulfide + H2O

3 entries

additional information

?

-

Staphylococcus aureus

P0A006

assays are performed with different arsenate concentrations and arsenate reductase concentrations in the presence of 0.42 microM Escherichia coli thioredoxin, 0.14 microM Escherichia coli thioredoxin reductase and 125 microM NADPH

639370

-

-

?

arsenate + thioredoxin

arsenite + thioredoxin disulfide + H2O

Staphylococcus aureus

P0A006

-

639368

-

-

?

arsenate + thioredoxin

arsenite + thioredoxin disulfide + H2O

Staphylococcus aureus

P0A006

the enzyme encoded by Staphylococcus aureus arsenic-resistance plasmid pI258 reduces intracellular arsenate to the more toxic arsenite, which is subsequently extruded from the cell

639370

-

-

?

arsenate + thioredoxin

arsenite + thioredoxin disulfide + H2O

Thermus thermophilus

-

-

745640

-

-

?