1.20.4.4: arsenate reductase (thioredoxin)
This is an abbreviated version!
For detailed information about arsenate reductase (thioredoxin), go to the full flat file.
Reaction
Synonyms
ARS, ArsC, ArsC1, ArsC1', ArsC3, arsenate reductase, Bs_ArsC, pI258 arsenate reductase, plasmid pI258 arsenate reductase, Sa_ArsC, Strop634, thioredoxin-arsenate reductase complex, thioredoxin-coupled arsenate reductase, Trx-coupled arsenate reductase
ECTree
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Cofactor
Cofactor on EC 1.20.4.4 - arsenate reductase (thioredoxin)
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thioredoxin
interaction between thioredoxin and the enzyme pI258 arsenate reductase. Thioredoxin converts oxidized ArsC back towards its initial reduced state
ArsC couples to thioredoxin, thioredoxin reductase, and NADPH to be enzymatically active
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additional information
purified enzyme reduces radioactive arsenate to arsenite when coupled to thioredoxin, thioredoxin reductase, and NADPH. All three protein components, arsenate reductase, thioredoxin, and thioredoxin reductase, are required for arsenate reduction. Glutaredoxin and reduced glutathione do not stimulate arsenate reduction
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