1.2.7.8: indolepyruvate ferredoxin oxidoreductase
This is an abbreviated version!
For detailed information about indolepyruvate ferredoxin oxidoreductase, go to the full flat file.
Word Map on EC 1.2.7.8
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1.2.7.8
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hyperthermophilic
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archaeon
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pyrococcus
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2-oxoglutarate
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transamination
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air
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thermococcus
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analysis
- 1.2.7.8
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hyperthermophilic
- archaeon
- pyrococcus
- 2-oxoglutarate
-
transamination
- air
-
thermococcus
- analysis
Reaction
+ + 2 oxidized ferredoxin = + + 2 reduced ferredoxin + 2 H+
Synonyms
3-(indol-3-yl)pyruvate synthase (ferredoxin), arylpyruvate-ferredoxin oxidoreductase, hydroxyphenylpyruvate oxidase, indolepyruvate oxidase, indolepyruvate-ferredoxin oxidoreductase, indolepyruvate:Fd oxidoreductase, IOR, phenylpyruvate oxidase, VOR
ECTree
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Reaction
Reaction on EC 1.2.7.8 - indolepyruvate ferredoxin oxidoreductase
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(indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+
this enzyme, which is found in archaea, is one of four 2-oxoacid oxidoreductases that are differentiated by their abilities to oxidatively decarboxylate different 2-oxoacids and form their CoA derivatives (see aslo EC 1.2.7.1, pyruvate synthase, EC 1.2.7.7., 2-oxoisovalerate ferredoxin reductase and EC 1.2.7.9, 2-oxoglutarate ferredoxin oxidoreductase). Contains thiamine diphosphate and [4Fe-4S] clusters. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and p-hydroxyphenylpyruvate as substrates
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