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1.2.7.8: indolepyruvate ferredoxin oxidoreductase

This is an abbreviated version!
For detailed information about indolepyruvate ferredoxin oxidoreductase, go to the full flat file.

Word Map on EC 1.2.7.8

Reaction

(indol-3-yl)pyruvate
+
CoA
+ 2 oxidized ferredoxin =
S-2-(indol-3-yl)acetyl-CoA
+
CO2
+ 2 reduced ferredoxin + 2 H+

Synonyms

3-(indol-3-yl)pyruvate synthase (ferredoxin), arylpyruvate-ferredoxin oxidoreductase, hydroxyphenylpyruvate oxidase, indolepyruvate oxidase, indolepyruvate-ferredoxin oxidoreductase, indolepyruvate:Fd oxidoreductase, IOR, phenylpyruvate oxidase, VOR

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.7 With an iron-sulfur protein as acceptor
                1.2.7.8 indolepyruvate ferredoxin oxidoreductase

General Information

General Information on EC 1.2.7.8 - indolepyruvate ferredoxin oxidoreductase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
Q6LZB6; Q6LZB5, Q6M0F5; Q6M0F6
Methanococcus maripaludis has two IOR homologs. A deletion mutant for one of these homologs contains 76, 74, and 42% lower activity for phenylpyruvate, p-hydroxyphenylpyruvate, and indolepyruvate oxidation, respectively, than the wild type. Growth of this mutant in minimal medium is inhibited by the aryl acids, but the aromatic amino aciuds partially restore growth