1.2.7.4: anaerobic carbon-monoxide dehydrogenase

This is an abbreviated version!
For detailed information about anaerobic carbon-monoxide dehydrogenase, go to the full flat file.

Reaction

Synonyms

acetyl coenzyme A synthase/carbon monoxide dehydrogenase, acetyl-CoA synthase/carbon monoxide dehydrogenase, ACS/CODH, Carbon dioxide/carbon monoxide oxidoreductase, Carbon monoxide dehydrogenase, carbon monoxide dehydrogenase-corrinoid enzyme complex, carbon monoxide dehydrogenase/acetyl-CoA synthase, Carbon monoxide oxidoreductase, Cdh, CO dehydrogenase, CO dehydrogenase complex, CO dehydrogenase complex II, CO dehydrogenase II, CO dehydrogenase/acetyl-CoA synthase, Co-DG, CO-DH, CODH, CODH II, CODH-II, CODH/ACS, CODHACS, CODHase, CODHII, coos, Dehydrogenase, carbon monoxide, EC 1.2.99.2, monoxide dehydrogenase/acetyl-CoA synthase, Ni,Fe-CODH, Ni,Fe-dependent carbon monoxide dehydrogenase, Ni-CODH, Ni-containing carbon monoxide dehydrogenase, Ni-Fe carbon monoxide dehydrogenase II

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.7 With an iron-sulfur protein as acceptor

                1.2.7.4 anaerobic carbon-monoxide dehydrogenase

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Results	in table
11	Activating Compound
8614	AA Sequence
1	Application
1	CAS Registry Number
12	Cloned(Commentary)
18	Cofactor
8	Crystallization (Commentary)
2	Expression
10	General Information
5	General Stability
63	Inhibitors
3	kcat/KM [mM/s]
18	Ki Value [mM]
32	KM Value [mM]
3	Localization
103	Metals/Ions
82	Molecular Weight [Da]
38	Natural Substrates/ Products (Substrates)
170	Organism
11	Oxidation Stability
11	Pathway
75	PDB ID
19	pH Optimum
5	pH Range
1	pH Stability
38	Protein Variants
28	Purification (Commentary)
13	Reaction
3	Reaction Type
135	Reference
12	Source Tissue
46	Specific Activity [micromol/min/mg]
6	Storage Stability
182	Substrates and Products (Substrate)
36	Subunits
138	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
10	Temperature Stability [°C]
18	Turnover Number [1/s]

Organism

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Organism on EC 1.2.7.4 - anaerobic carbon-monoxide dehydrogenase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Acetobacterium woodii

-

390451, 390458

-

-

brenda

Aeropyrum pernix

-

725052

-

-

brenda

Aeropyrum pernix TB5

-

725052

-

-

brenda

Afipia carboxidovorans

2 entries

Archaeoglobus fulgidus

-

390471, 721441, 723991

-

-

brenda

Archaeoglobus fulgidus 7324

-

723991

-

-

brenda

Archaeoglobus lithotrophicus

-

721441

-

-

brenda

Archaeoglobus lithotrophicus TF-2

-

721441

-

-

brenda

archaeon

phylogenomic study of monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) in over 6400 archaeal and bacterial genomes

758239

-

-

brenda

Autotrophic methanogenic bacterium

-

390455

-

-

brenda

bacterium

phylogenomic study of monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) in over 6400 archaeal and bacterial genomes

758239

-

-

brenda

Bradyrhizobium japonicum

gram-negativ soil bacterium

390484

-

-

brenda

Carboxydothermus hydrogenoformans

9 entries

Carboxydothermus hydrogenoformans DSM 6008

-

724590

Q9F8A8

Uniprot

brenda

Carboxydothermus hydrogenoformans Z-2901 / DSM 6008

strain Z-2901 (DSM 6008)

687538

-

-

brenda

Citrobacter amalonaticus

-

740543

-

-

brenda

Citrobacter amalonaticus Y19

-

740543

-

-

brenda

Clostridium carboxidivorans

-

762635

-

-

brenda

Clostridium pasteurianum

-

390451

-

-

brenda

Desulfotomaculum nigrificans

-

740945

-

-

brenda

Ferroglobus placidus

chemolithoautotrophic

721443

-

-

brenda

Ferroglobus placidus DSM 10642

chemolithoautotrophic

721443

-

-

brenda

Hydrogenophaga pseudoflava

-

390483

-

-

brenda

Leadbettera azotonutricia

-

726272

F5YDA7

UniProt

brenda

Leadbettera azotonutricia ZAS-9

-

726272

F5YDA7

UniProt

brenda

Methanococcus maripaludis

more than threefold induction of enzyme activity and increase in enzyme expression in a mutant lacking the membrane-bound energy-conserving hydrogenase Ehb

674264

-

-

brenda

Methanococcus vannielii

-

390450

-

-

brenda

Methanosarcina barkeri

-

390449, 390458, 390465, 390474, 727713, 727806

-

-

brenda

Methanosarcina barkeri DSM 800

-

727806

-

-

brenda

Methanosarcina mazei

strain Gö1

390463

-

-

brenda

Methanosarcina thermophila

2 entries

Methanosarcina thermophila TM-1

-

727715

-

-

brenda

Methanothermobacter thermautotrophicus

-

390456, 390458

-

-

brenda

Methanothrix soehngenii

-

390473

-

-

brenda

Moorella thermoacetica

8 entries

Mycobacterium sp.

2 entries

Mycobacterium sp. DSM 3803 / JC1

-

684871

-

-

brenda

Mycobacterium sp. JC1 DSM 3803

2 entries

Mycobacterium tuberculosis

-

684871

-

-

brenda

Mycobacterium tuberculosis H37Ra / ATCC 25177

-

684871

-

-

brenda

Mycobacterium tuberculosis TMC 326 / H37Ra-INH-R / ATCC 35835

-

684871

-

-

brenda

Mycolicibacterium vaccae

strain ATCC 15483

684871

-

-

brenda

no activity in Methanobrevibacter ruminantium

-

390455

-

-

brenda

no activity in Methanobrevibacter smithii

-

390455

-

-

brenda

no activity in Methanococcus voltae

-

390455

-

-

brenda

no activity in Methanospirillum hungatei

-

390455

-

-

brenda

Rhodospirillum rubrum

2 entries

Roseibium aggregatum

large subunit, fragment; synonym Stappia aggregata

684549

Q7X0G3

UniProt

brenda

Stappia carboxidovorans

2 entries

Stappia conradae

large subunit, fragment

684549

A1E2F7

UniProt

brenda

Stappia kahanamokuae

large subunit, fragment

684549

A1E2G2

UniProt

brenda

Stappia meyerae

-

684549

-

-

brenda

Stappia sp.

large subunit, fragment

684549

Q7X0G8

UniProt

brenda

Stappia sp. KB812

large subunit, fragment; strain KB812

684549

Q7X0G9

UniProt

brenda

Stappia sp. KB902

large subunit, fragment

684549

Q7X0G8

UniProt

brenda

Stappia sp. M8

large subunit, fragment; strain M8

684549

Q7X0G5

UniProt

brenda

Stappia stellulata

large subunit, fragment

684549

Q7X0G2

UniProt

brenda

synthetic construct

2 entries

Thermacetogenium phaeum

grows on acetate if cocultured with hydrogen-consuming methanogenic partner Methanothermobacter thermautrophicus

674239

-

-

brenda

Treponema primitia

-

726272

F5YMN6, F8TH35

UniProt

brenda

Treponema primitia ZAS-1

-

726272

F8TH35

UniProt

brenda

Treponema primitia ZAS-2

-

726272

F5YMN6

UniProt

brenda

Treponema sp.

-

726272

F8TH37, F8TH38, F8TH39

UniProt

brenda

Treponema sp. ZAS-5

-

726272

F8TH37

UniProt

brenda

Treponema sp. ZAS-6

-

726272

F8TH38

UniProt

brenda

Treponema sp. ZAS-8

-

726272

F8TH39

UniProt

brenda

Afipia carboxidovorans

-

390479, 390482, 657190, 712158

-

-

brenda

Afipia carboxidovorans

P19919 large subunit, P19920 medium subunit, P19921 small subunit

725197, 725392

P19919; P19920; P19921

UniProt

brenda

Carboxydothermus hydrogenoformans

-

655792, 684432

-

-

brenda

Carboxydothermus hydrogenoformans

-

690057, 712242

Q9F8A8

Uniprot

brenda

Carboxydothermus hydrogenoformans

-

712750

-

-

brenda

Carboxydothermus hydrogenoformans

-

724590

Q9F8A8

Uniprot

brenda

Carboxydothermus hydrogenoformans

-

740344

-

-

brenda

Carboxydothermus hydrogenoformans

enzyme CooS in complex with an electron transfer protein CooF and a membrane bound [Ni-Fe] hydrogenase

655446

-

-

brenda

Carboxydothermus hydrogenoformans

hydrogenogenic bacterium

390485

-

-

brenda

Carboxydothermus hydrogenoformans

strain DSMZ 6008

685261

-

-

brenda

Carboxydothermus hydrogenoformans

strain Z-2901 (DSM 6008)

687538

-

-

brenda

Methanosarcina thermophila

-

390470, 390472, 390478, 727715

-

-

brenda

Methanosarcina thermophila

strain DSM 521

687803

-

-

brenda

Moorella thermoacetica

-

390451, 390452, 390453, 390454, 390457, 390458, 390459, 390460, 390461, 390462, 390467, 390468, 390469, 390475, 390476, 390480, 390481, 654754, 655797, 674925, 684432, 685091, 687824

-

-

brenda

Moorella thermoacetica

ATCC 39073

390452

-

-

brenda

Moorella thermoacetica

bifunctional acetyl-coenzyme A synthase/carbon monoxide dehydrogenase, isolated alpha subunit

655801

-

-

brenda

Moorella thermoacetica

bifunctional enzyme with carbon-monoxide dehydrogenase/acetyl coenzyme A synthase activity

656297

-

-

brenda

Moorella thermoacetica

CODH/ACS subunit beta; formerly Clostridium thermoaceticum strain ATCC 39073

696351

P27989

UniProt

brenda

Moorella thermoacetica

formerly Clostridium thermoaceticum

390452, 390454, 390459

-

-

brenda

Moorella thermoacetica

formerly Clostridium thermoaceticum strain ATCC 39073

685228

-

-

brenda

Moorella thermoacetica

strain DSM 521

687803

-

-

brenda

Mycobacterium sp.

-

684871, 712300

-

-

brenda

Mycobacterium sp.

large, medium and small subunit

712970

D5G1Y2; D5G1Y0; D5G1Y1

UniProt

brenda

Mycobacterium sp. JC1 DSM 3803

-

712300

-

-

brenda

Mycobacterium sp. JC1 DSM 3803

large, medium and small subunit

712970

D5G1Y2; D5G1Y0; D5G1Y1

UniProt

brenda

Rhodospirillum rubrum

-

390464, 390466, 390486, 654737, 655797, 656296, 672350, 674921, 684432

-

-

brenda

Rhodospirillum rubrum

purple nonsulfur bacterium, the enzyme exists in the forms, I and II, which differ in metal content

390448

-

-

brenda

Stappia carboxidovorans

-

684549

-

-

brenda

Stappia carboxidovorans

large subunit, fragment; strain M4

684549

Q7X0G6

UniProt

brenda

synthetic construct

-

674000

-

-

brenda

synthetic construct

analogue of the C-cluster of Carboxydothermus hydrogenoformans

674148

-

-

brenda