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1.2.7.11: 2-oxoacid oxidoreductase (ferredoxin)

This is an abbreviated version!
For detailed information about 2-oxoacid oxidoreductase (ferredoxin), go to the full flat file.

Word Map on EC 1.2.7.11

Reaction

a 2-oxocarboxylate
+
CoA
 + 2 oxidized ferredoxin =
an acyl-CoA
 +
CO2
 + 2 reduced ferredoxin + 2 H+

Synonyms

2-ketoacid:ferredoxin oxidoreductase, 2-oxoacid: ferredoxin oxidoreductase, 2-oxoacid:ferredoxin oxidoreductase, 2-oxoacid:ferredoxin oxidoreductases, Ape1473/1472, KOR, OFOR, OFOR1, OFOR2, PFOR, Saci_2306, Saci_2307, StOFOR, StOFOR1, StOFOR2

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.7 With an iron-sulfur protein as acceptor
                1.2.7.11 2-oxoacid oxidoreductase (ferredoxin)

Reference

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Reference on EC 1.2.7.11 - 2-oxoacid oxidoreductase (ferredoxin)

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kerscher, L.; Oesterhelt, D.
Purification and properties of two 2-oxoacid:ferredoxin oxidoreductases from Halobacterium halobium
Eur. J. Biochem.
116
587-594
1981
Halobacterium salinarum
Manually annotated by BRENDA team
Zhang, Q.; Iwaaki, T.; Wakagi, T.; Oshima, T.
2-Oxoacid:ferredoxin oxidoreductase from the thermoacidophilic archaeon, Sulfolobus sp. strain 7
J. Biochem.
120
587-599
1996
Sulfolobus sp. (P72578 and P72579), Sulfolobus sp., Sulfolobus sp. 7 (P72578 and P72579)
Manually annotated by BRENDA team
Fukuda, E.; Wakagi, T.
Substrate recognition by 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus sp. strain 7
Biochim. Biophys. Acta
1597
74-80
2002
Sulfolobus sp., Sulfolobus sp. 7
Manually annotated by BRENDA team
Nishizawa, Y.; Yabuki, T.; Fukuda, E.; Wakagi, T.
Gene expression and characterization of two 2-oxoacid:ferredoxin oxidoreductases from Aeropyrum pernix K1
FEBS Lett.
579
2319-2322
2005
Aeropyrum pernix
Manually annotated by BRENDA team
Park, Y.J.; Yoo, C.B.; Choi, S.Y.; Lee, H.B.
Purifications and characterizations of a ferredoxin and its related 2-oxoacid:ferredoxin oxidoreductase from the hyperthermophilic archaeon, Sulfolobus solfataricus P1
J. Biochem. Mol. Biol.
39
46-54
2006
Saccharolobus solfataricus, Saccharolobus solfataricus P1, Saccharolobus solfataricus DSM 1616
Manually annotated by BRENDA team
Luo, J.; Fukuda, E.; Takase, H.; Fushinobu, S.; Shoun, H.; Wakagi, T.
Identification of the lysine residue responsible for coenzyme A binding in the heterodimeric 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus tokodaii, a thermoacidophilic archaeon, using 4-fluoro-7-nitrobenzofurazan as an affinity label
Biochim. Biophys. Acta
1794
335-340
2009
Sulfurisphaera tokodaii
Manually annotated by BRENDA team
Fukuda, E.; Kino, H.; Matsuzawa, H.; Wakagi, T.
Role of a highly conserved YPITP motif in 2-oxoacid:ferredoxin oxidoreductase: heterologous expression of the gene from Sulfolobus sp.strain 7, and characterization of the recombinant and variant enzymes
Eur. J. Biochem.
268
5639-5646
2001
Sulfolobus sp., Sulfolobus sp. 7
Manually annotated by BRENDA team
Yan, Z.; Fushinobu, S.; Wakagi, T.
Four Cys residues in heterodimeric 2-oxoacid:ferredoxin oxidoreductase are required for CoA-dependent oxidative decarboxylation but not for a non-oxidative decarboxylation
Biochim. Biophys. Acta
1844
736-743
2014
Sulfurisphaera tokodaii
Manually annotated by BRENDA team
Iwasaki, T.; Wakagi, T.; Oshima, T.
Ferredoxin-dependent redox system of a thermoacidophilic archaeon, Sulfolobus sp. strain 7. Purification and characterization of a novel reduced ferredoxin-reoxidizing iron-sulfur flavoprotein
J. Biol. Chem.
270
17878-17883
1995
Sulfolobus sp., Sulfolobus sp. 7
Manually annotated by BRENDA team
Iwasaki, T.; Oshima, T.
Ferredoxin and related enzymes from Sulfolobus
Methods Enzymol.
334
3-22
2001
Sulfolobus sp. (P72578 and P72579), Sulfolobus sp. 7 (P72578 and P72579)
Manually annotated by BRENDA team
Yan, Z.; Maruyama, A.; Arakawa, T.; Fushinobu, S.; Wakagi, T.
Crystal structures of archaeal 2-oxoacid:ferredoxin oxidoreductases from Sulfolobus tokodaii
Sci. Rep.
6
33061
2016
Sulfurisphaera tokodaii (Q96XT2 and Q96XT4), Sulfurisphaera tokodaii (Q96XT4), Sulfurisphaera tokodaii (Q96Y66 and Q96Y68), Sulfurisphaera tokodaii (Q96Y68), Sulfurisphaera tokodaii, Sulfurisphaera tokodaii 7 (Q96XT4), Sulfurisphaera tokodaii 7 (Q96Y68), Sulfurisphaera tokodaii DSM 16993 (Q96XT2 and Q96XT4), Sulfurisphaera tokodaii DSM 16993 (Q96Y66 and Q96Y68)
Manually annotated by BRENDA team
Gibson, M.I.; Chen, P.Y.; Drennan, C.L.
A structural phylogeny for understanding 2-oxoacid oxidoreductase function
Curr. Opin. Struct. Biol.
41
54-61
2016
Desulfocurvibacter africanus, Saccharolobus solfataricus
Manually annotated by BRENDA team
Li, B.; Elliott, S.
The catalytic bias of 2-oxoacid: ferredoxin oxidoreductase in CO2: evolution and reduction through a ferredoxin-mediated electrocatalytic assay
Electrochim. Acta
199
349-356
2016
Desulfocurvibacter africanus, Hydrogenobacter thermophilus
-
Manually annotated by BRENDA team
Yokooji, Y.; Sato, T.; Fujiwara, S.; Imanaka, T.; Atomi, H.
Genetic examination of initial amino acid oxidation and glutamate catabolism in the hyperthermophilic archaeon Thermococcus kodakarensis
J. Bacteriol.
195
1940-1948
2013
Thermococcus kodakarensis
Manually annotated by BRENDA team
Witt, A.; Pozzi, R.; Diesch, S.; Haedicke, O.; Grammel, H.
New light on ancient enzymes - in vitro CO2 fixation by pyruvate synthase of Desulfovibrio africanus and Sulfolobus acidocaldarius
FEBS J.
286
4494-4508
2019
Sulfolobus acidocaldarius (Q4J6I9 and Q4J6I8), Sulfolobus acidocaldarius DSM 639 (Q4J6I9 and Q4J6I8)
Manually annotated by BRENDA team