1.2.3.15: (methyl)glyoxal oxidase
This is an abbreviated version!
For detailed information about (methyl)glyoxal oxidase, go to the full flat file.
Reaction
Synonyms
GLOX, Glox2, Glox3, GLX, Glx1, GLX2, methylglyoxal oxidase, MYCTH_2294895
ECTree
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Metals Ions
Metals Ions on EC 1.2.3.15 - (methyl)glyoxal oxidase
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copper
protein contains a radical-coupled copper complex, a mononuclear Cu(II) center with an axial coordination
Cu2+
additional information
no activation is observed with Mg2+, Zn2+, Fe2+, or Mn2+
Cu2+
full activation takes more than 1 h with 1 mM CuSO4 at pH 6.0
Cu2+
-
enzyme is a copper radical oxidase. Residues comprising the copper coordinating active site and the radical redox site are Cys228, Tyr272, Tyr495, His496, and His581