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1.2.1.90: glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

D-glyceraldehyde 3-phosphate
+
NAD(P)+
 +
H2O
=
3-phospho-D-glycerate
 +
NAD(P)H
 + 2 H+

Synonyms

GAPN, More, NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase, NAD+-dependent non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase, non-phosphorylating Ga3PDHase, non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase, nonphosphorylating NAD+-dependent GAPN

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

KM Value

KM Value on EC 1.2.1.90 - glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.02 - 2.2
D-glyceraldehyde 3-phosphate
3
L-Glyceraldehyde 3-phosphate
about, pH 8.5, 30°C, recombinant enzyme, with NADP+
0.4 - 3.3
NAD+
0.23
NADP+
pH 8.5, 30°C, recombinant enzyme, with succinate semialdehyde
additional information
D-glyceraldehyde 3-phosphate
the saturation with D-glyceraldehyde 3-phosphate follows classical Michaelis-Menten kinetics, showing half-maximal saturation at 50 mM. A definite Km for the free aldehyde, the presumed substrate of the enzyme, cannot be given because the portion of the free aldehyde in aqueous solution could not be determined at 70 °C