1.2.1.86: geranial dehydrogenase

This is an abbreviated version!
For detailed information about geranial dehydrogenase, go to the full flat file.

Reaction

Synonyms

citral dehydrogenase I, citral dehydrogenase II, GADH, geoB, NAD+-dependent citral dehydrogenase

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.86 geranial dehydrogenase

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Results	in table
196	AA Sequence
1	Cloned(Commentary)
2	Cofactor
2	General Information
10	KM Value [mM]
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
6	Organism
4	Pathway
1	pH Optimum
1	pH Range
2	pI Value
1	Purification (Commentary)
1	Reaction
6	Reference
3	Source Tissue
3	Specific Activity [micromol/min/mg]
12	Substrates and Products (Substrate)
3	Subunits
12	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 1.2.1.86 - geranial dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

alpha-methyl cinnamaldehyde + NAD+ + H2O

alpha-methyl cinnamic acid + NADH + H+

Persicaria minor

-

isoform citral dehydrogenase I shows 62% activity compared to citral, isoform citral dehydrogenase II shows 85% activity compared to citral

761737

-

-

?

citral + NAD+ + H2O

geranic acid + NADH + H+

2 entries

geranial + H2O + NAD+

geranate + NADH + H+

5 entries

geranial + NAD+ + H2O

geranic acid + NADH + H+

Persicaria minor

-

-

761737

-

-

?

S-perillyl aldehyde + NAD+ + H2O

perillic acid + NADH + H+

Persicaria minor

-

isoform citral dehydrogenase I shows 37% activity compared to citral, isoform citral dehydrogenase II shows 54% activity compared to citral

761737

-

-

?

trans-cinnamaldehyde + NAD+ + H2O

cinnamic acid + NADH + H+

Persicaria minor

-

isoform citral dehydrogenase I shows 73% activity compared to citral, isoform citral dehydrogenase II shows 87% activity compared to citral

761737

-

-

?

additional information

?

-

Persicaria minor

-

the enzyme shows no reaction with NADP+. No reduction reaction is observed either with NADH or NADPH as a coenzyme

761737

-

-

-

citral + NAD+ + H2O

geranic acid + NADH + H+

Persicaria minor

-

-

761737

-

-

ir

citral + NAD+ + H2O

geranic acid + NADH + H+

Persicaria minor

-

100% activity

761737

-

-

ir

geranial + H2O + NAD+

geranate + NADH + H+

Castellaniella defragrans

-

-

719178

-

-

?

geranial + H2O + NAD+

geranate + NADH + H+

Castellaniella defragrans

-

-

718643

-

-

ir

geranial + H2O + NAD+

geranate + NADH + H+

Castellaniella defragrans 65Phen

-

-

719178

-

-

?

geranial + H2O + NAD+

geranate + NADH + H+

Penicillium digitatum

-

geranial is partially transformed into geranic acid by NAD+-dependent citral dehydrogenase activity

718657

-

-

?

geranial + H2O + NAD+

geranate + NADH + H+

Penicillium digitatum ATCC 201167

-

geranial is partially transformed into geranic acid by NAD+-dependent citral dehydrogenase activity

718657

-

-

?