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1.2.1.8: betaine-aldehyde dehydrogenase

This is an abbreviated version!
For detailed information about betaine-aldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.8

Reaction

Betaine aldehyde
+
NAD+
+
H2O
=
betaine
+
NADH
+ 2 H+

Synonyms

AcBADH, ALD10, aldehyde dehydrogenase, ALDH10, ALDH10A8, ALDH10A9, AMADH, AMADH1, aminoaldehyde dehydrogenase, BADH, BADH1, BADH2, badh2-E2, badh2-E7, betaine aldehyde dehydrogenase, betaine aldehyde dehydrogenase 1, betaine aldehyde dehydrogenase 1, chloroplastic, betaine aldehyde dehydrogenase 2, betaine aldehyde dehydrogenase, chloroplastic, betaine aldehyde oxidase, betaine aldehyde: NAD(P)+ oxidoreductase, betaine aldehyde: NAD+ oxidoreductase, betaine aldehyde:NAD(P)+ oxidoreductase, betaine aldehyde:NAD+ oxidoreductase, betaine-aldehyde dehydrogenase, BetB, dehydrogenase, betaine aldehyde, JcBD1, LcBADH, More, OsALDH10-1, OsALDH10-2, OsBADH1, OsBADH2, PaBADH, PaBADH2, pkBADH, PND BADH2, SACOL2628, YdcW, ZBD1, Zoysia betaine aldehyde dehydrogenase 1

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.8 betaine-aldehyde dehydrogenase

General Stability

General Stability on EC 1.2.1.8 - betaine-aldehyde dehydrogenase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
addition of glycerol and 2-mercaptoethanol effectively stabilizes the enzyme
-
at the optimum pH of 8.0 the enzyme is inactivated by dilution, it is stable at pH 6.5 even at very low concentrations
-
complete loss of activity when dialyzed against 10 mM buffer, pH 8.0, addition of 20% glycerol stabilizes
-
dialysis for 5 days against 0.1 M buffer, pH 7.4, at 4°C, stable
-
salt-tolerant enzyme retains 50% of its initial activity at 1.2 M K+
-
the enzyme is stable in absence of K+ even at very low enzyme concentrations
-
total RNA of leaves subjected to RT-PCR analysis to examine the influence of environmental stress like drought, salt or heat on BADH expression. Results showed tha JcBD1 gene transcripts of those plants exposed to 30% PEG, 300 mM NaCl or 50°C heat stress were obviously higher than that of the control plants. JcBD1 mRNA levels in stress treated leaved are increased by 79% or more, as compared with the control, which strongly confirms that mRNA expression are relative to abiotic stress.