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1.2.1.79: succinate-semialdehyde dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about succinate-semialdehyde dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.2.1.79

Reaction

succinate semialdehyde
+
NADP+
 +
H2O
=
succinate
 +
NADPH
 + 2 H+

Synonyms

AbSSADH, ALDH21, all3556, ApSSADH, gabD, GabD1, NADP+-dependent SSADH, NADP+-dependent succinic semialdehyde dehydrogenase, NADP-dependent succinic semialdehyde dehydrogenase, PpSSALDH, slr0370, Sp2771, SpSSADH, SSADH, SSADH-II, SSALDH, SSO1842, succinic semialdehy de dehydrogenase, succinic semialdehyde dehydrogenase, SYNPCC7002_A2771, SySSADH

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)

Reference

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Reference on EC 1.2.1.79 - succinate-semialdehyde dehydrogenase (NADP+)

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sanchez, M.; Fernandez, J.; Martin, M.; Gibello, A.; Garrido-Pertierra, A.
Purification and properties of two succinic semialdehyde dehydrogenases from Klebsiella pneumoniae
Biochim. Biophys. Acta
990
225-231
1989
Klebsiella pneumoniae
Manually annotated by BRENDA team
Tokunaga, M.; Nakano, Y.; Kitaoka, S.
Separation and properties of the NAD-linked and NADP-linked isozymes of succinic semialdehyde dehydrogenase in Euglena gracilis z
Biochim. Biophys. Acta
429
55-62
1976
Euglena gracilis
Manually annotated by BRENDA team
Lutke-Eversloh, T.; Steinbuchel, A.
Biochemical and molecular characterization of a succinate semialdehyde dehydrogenase involved in the catabolism of 4-hydroxybutyric acid in Ralstonia eutropha
FEMS Microbiol. Lett.
181
63-71
1999
Cupriavidus necator (Q9RBF6)
Manually annotated by BRENDA team
Jaeger, M.; Rothacker, B.; Ilg, T.
Saturation transfer difference NMR studies on substrates and inhibitors of succinic semialdehyde dehydrogenases
Biochem. Biophys. Res. Commun.
372
400-406
2008
Escherichia coli (P25526)
Manually annotated by BRENDA team
Ahn, J.-W.; Kim, Y.-G.; Kim, K.-J.
Crystal structure of non-redox regulated SSADH from Escherichia coli
Biochem. Biophys. Res. Commun.
392
106-111
2010
Escherichia coli
Manually annotated by BRENDA team
Cozzani, I.; Fazio, A.M.; Felici, E.; Barletta, G.
Separation and characterization of NAD- and NADP-specific succinate-semialdehyde dehydrogenase from Escherichia coli K-12 3300
Biochim. Biophys. Acta
613
309-317
1980
Escherichia coli K-12
Manually annotated by BRENDA team
Sanchez, M.; Alvarez, M.A.; Balana, R.; Garrido-Pertierra, A.
Properties and functions of two succinic-semialdehyde dehydrogenases from Pseudomonas putida
Biochim. Biophys. Acta
953
249-257
1988
Pseudomonas putida
Manually annotated by BRENDA team
Bartsch, K.; von Johnn-Marteville, A.; Schulz, A.
Molecular analysis of two genes of the Escherichia coli gab cluster: nucleotide sequence of the glutamate:succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD)
J. Bacteriol.
172
7035-7042
1990
Escherichia coli
Manually annotated by BRENDA team
Langendorf, C.G.; Key, T.L.; Fenalti, G.; Kan, W.T.; Buckle, A.M.; Caradoc-Davies, T.; Tuck, K.L.; Law, R.H.; Whisstock, J.C.
The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions
PLoS One
5
e9280
2010
Escherichia coli (P25526), Escherichia coli K-12 (P25526), Escherichia coli MC1061 (P25526)
Manually annotated by BRENDA team
Esser, D.; Kouril, T.; Talfournier, F.; Polkowska, J.; Schrader, T.; Bräsen, C.; Siebers, B.
Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus
Extremophiles
17
205-216
2013
Saccharolobus solfataricus (Q97XA5), Saccharolobus solfataricus P2 (Q97XA5)
Manually annotated by BRENDA team
de Carvalho, L.P.; Ling, Y.; Shen, C.; Warren, J.D.; Rhee, K.Y.
On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis
Arch. Biochem. Biophys.
509
90-99
2011
Mycobacterium tuberculosis (P9WNX9), Mycobacterium tuberculosis H37Rv (P9WNX9)
Manually annotated by BRENDA team
Park, J.; Rhee, S.
Structural basis for a cofactor-dependent oxidation protection and catalysis of cyanobacterial succinic semialdehyde dehydrogenase
J. Biol. Chem.
288
15760-15770
2013
Synechococcus sp. (B1XMM6)
Manually annotated by BRENDA team
Yuan, Z.; Yin, B.; Wei, D.; Yuan, Y.R.
Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J. Struct. Biol.
182
125-135
2013
Synechococcus sp. (B1XMM6)
Manually annotated by BRENDA team
Jang, E.H.; Park, S.A.; Chi, Y.M.; Lee, K.S.
Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes
Biochem. Biophys. Res. Commun.
461
487-493
2015
Streptococcus pyogenes (A0A0J9X1M8), Streptococcus pyogenes MGAS1882 (A0A0J9X1M8)
Manually annotated by BRENDA team
Jang, E.H.; Park, S.A.; Chi, Y.M.; Lee, K.S.
Kinetic and structural characterization for cofactor preference of succinic semialdehyde dehydrogenase from Streptococcus pyogenes
Mol. Cells
37
719-726
2014
Streptococcus pyogenes (A0A0J9X1M8), Streptococcus pyogenes MGAS1882 (A0A0J9X1M8)
Manually annotated by BRENDA team
Jang, E.H.; Park, S.A.; Chi, Y.M.; Lee, K.S.
Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes
Biochem. Biophys. Res. Commun.
461
487-493
2015
Streptococcus pyogenes (A0A0J9X1M8), Streptococcus pyogenes MG-AS1882 (A0A0J9X1M8)
Manually annotated by BRENDA team
Park, J.; Rhee, S.
Structural basis for a cofactor-dependent oxidation protection and catalysis of cyanobacterial succinic semialdehyde dehydrogenase
J. Biol. Chem.
288
15760-15770
2013
Synechococcus sp. (B1XMM6), Synechococcus sp. ATCC 27264 (B1XMM6)
Manually annotated by BRENDA team
Yuan, Z.; Yin, B.; Wei, D.; Yuan, Y.R.
Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J. Struct. Biol.
182
125-135
2013
Synechococcus sp. PCC 7002 (B1XMM6)
Manually annotated by BRENDA team
Kim, H.T.; Khang, T.U.; Baritugo, K.A.; Hyun, S.M.; Kang, K.H.; Jung, S.H.; Song, B.K.; Park, K.; Oh, M.K.; Kim, G.B.; Kim, H.U.; Lee, S.Y.; Park, S.J.; Joo, J.C.
Metabolic engineering of Corynebacterium glutamicum for the production of glutaric acid, a C5 dicarboxylic acid platform chemical
Metab. Eng.
51
99-109
2019
Corynebacterium glutamicum (A0A1Q6BLU5)
Manually annotated by BRENDA team
Ito, S.; Osanai, T.
Unconventional biochemical regulation of the oxidative pentose phosphate pathway in the model cyanobacterium Synechocystis sp. PCC 6803
Biochem. J.
477
1309-1321
2020
Synechocystis sp. PCC 6803 (Q55585), Synechocystis sp. PCC 6803
Manually annotated by BRENDA team
Phonbuppha, J.; Maenpuen, S.; Munkajohnpong, P.; Chaiyen, P.; Tinikul, R.
Selective determination of the catalytic cysteine pKa of two-cysteine succinic semialdehyde dehydrogenase from Acinetobacter baumannii using burst kinetics and enzyme adduct formation
FEBS J.
285
2504-2519
2018
Acinetobacter baumannii (A0A0D5YDF1), Acinetobacter baumannii
Manually annotated by BRENDA team
Wang, X.; Lai, C.; Lei, G.; Wang, F.; Long, H.; Wu, X.; Chen, J.; Huo, G.; Li, Z.
Kinetic characterization and structural modeling of an NADP+-dependent succinic semialdehyde dehydrogenase from Anabaena sp. PCC7120
Int. J. Biol. Macromol.
108
615-624
2018
Nostoc sp. PCC 7120 = FACHB-418 (Q8YR92)
Manually annotated by BRENDA team
Kopecna, M.; Vigouroux, A.; Vilim, J.; Koncitikova, R.; Briozzo, P.; Hajkova, E.; Jaskova, L.; von Schwartzenberg, K.; Sebela, M.; Morera, S.; Kopecny, D.
The ALDH21 gene found in lower plants and some vascular plants codes for a NADP+-dependent succinic semialdehyde dehydrogenase
Plant J.
92
229-243
2017
Physcomitrium patens (A9SS48), Physcomitrium patens
Manually annotated by BRENDA team