1.2.1.61: 4-hydroxymuconic-semialdehyde dehydrogenase

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For detailed information about 4-hydroxymuconic-semialdehyde dehydrogenase, go to the full flat file.

Reaction

Synonyms

4-HS dehydrogenase, 4-hydroxymuconic semialdehyde dehydrogenase, gamma-hydroxymuconic semialdehyde dehydrogenase, hAPE, HqdC, NAD dependent gamma-hydroxymuconic semialdehyde dehydrogenase, PdcG, pnpE

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.61 4-hydroxymuconic-semialdehyde dehydrogenase

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Results	in table
5	AA Sequence
2	Application
3	Cloned(Commentary)
4	Cofactor
1	Crystallization (Commentary)
2	Expression
6	General Information
2	Inhibitors
12	Metals/Ions
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
16	Organism
4	Pathway
2	pH Optimum
1	pH Range
1	pH Stability
9	Protein Variants
2	Purification (Commentary)
2	Reaction
3	Reaction Type
8	Reference
1	Source Tissue
4	Specific Activity [micromol/min/mg]
8	Substrates and Products (Substrate)
1	Subunits
19	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.2.1.61 - 4-hydroxymuconic-semialdehyde dehydrogenase

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4-hydroxymuconic semialdehyde + NAD+ + H2O

maleylacetate + NADH

Moraxella sp.

conversion of hydroquinone to beta-ketoadipic acid via 4-hydroxymuconic semialdehyde and maleyl acetic acid

288304

4-hydroxymuconic semialdehyde + NAD+ + H2O

maleylacetate + NADH + 2 H+

Pseudomonas sp. WBC-3

C1I208

742206