1.2.1.41: glutamate-5-semialdehyde dehydrogenase

This is an abbreviated version!
For detailed information about glutamate-5-semialdehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.41

1.2.1.41

cutis

paraplegia

1-pyrroline-5-carboxylate

progeroid

delta1-pyrroline-5-carboxylate

proba

1.5.1.12

medicine

Reaction

Synonyms

Aldh18a1, ALDH4, beta-glutamylphosphate reductase, dehydrogenase, glutamate semialdehyde, gamma glutamyl semialdehyde dehydrogenase, gamma-glutamyl phosphate reductase, gamma-GPR, GGSALDH, glutamate 5-semialdehyde dehydrogenase, glutamate semialdehyde dehydrogenase, Glutamate-5-semialdehyde dehydrogenase, glutamate-gamma-semialdehyde dehydrogenase, glutamic gamma-semialdehyde dehydrogenase, glutamic-gamma-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GPR, GSA dehydrogenase, OsALDH18-1, P5CS, pyrroline 5-carboxylate dehydrogenase, pyrroline-5-carboxylate synthase, pyrroline-5-carboxylate synthetase, reductase, gamma-glutamyl phosphate

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.41 glutamate-5-semialdehyde dehydrogenase

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Results	in table
2	Activating Compound
37908	AA Sequence
2	Application
1	CAS Registry Number
15	Cloned(Commentary)
26	Cofactor
1	Crystallization (Commentary)
142	Disease/ Diagnostics
1	General Stability
12	Inhibitors
2	Ki Value [mM]
11	KM Value [mM]
5	Localization
2	Metals/Ions
9	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
33	Organism
12	Pathway
42	PDB ID
6	pH Optimum
2	pH Range
2	pH Stability
4	Purification (Commentary)
1	Reaction
14	Reaction Type
31	Reference
27	Source Tissue
7	Specific Activity [micromol/min/mg]
4	Storage Stability
31	Substrates and Products (Substrate)
4	Subunits
60	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
3	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.2.1.41 - glutamate-5-semialdehyde dehydrogenase

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L-5-glutamyl phosphate + NADPH

2 entries

L-glutamate 5-semialdehyde + phosphate + NAD+

L-glutamyl 5-phosphate + NADH + H+

Thermus thermophilus

697283

L-glutamate 5-semialdehyde + phosphate + NADP+

L-glutamyl 5-phosphate + NADPH + H+

6 entries

additional information

Oryza sativa

Q941T1

ALDH superfamily represents a group of enzymes that catalyze the oxidation of endogenous and exogenous aldehydes to the corresponding carboxylic acids

698095