1.2.1.22: lactaldehyde dehydrogenase

This is an abbreviated version!
For detailed information about lactaldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.22

1.2.1.22

aldolase

l-lactate

l-rhamnose

glycol

l-fucose

dehydrogenases

1-phosphate

methylglyoxal

glycolaldehyde

nad+-dependent

l-1,2-propanediol

propanediol

non-phosphorylated

permease

dissimilate

dihydroxyacetone

Reaction

Synonyms

ALD, AldA, aldehyde dehyrogenase, ALDH, AN0544, AvLADH, dehydrogenase, lactaldehyde, L-lactaldehyde dehydrogenase, L-lactaldehyde:NAD oxidoreductase, Lactaldehyde dehydrogenase, LADH, MJ1411, More, NAD-dependent lactaldehyde dehydrogenase, nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase, PsLADH, SSO3117

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.22 lactaldehyde dehydrogenase

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Results	in table
4	Activating Compound
1351	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
25	Cofactor
2	Crystallization (Commentary)
2	Expression
13	General Information
2	General Stability
22	Inhibitors
4	kcat/KM [mM/s]
29	KM Value [mM]
1	Localization
4	Metals/Ions
10	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
35	Organism
9	Pathway
18	PDB ID
5	pH Optimum
2	pH Range
1	pH Stability
26	Protein Variants
13	Purification (Commentary)
1	Reaction
3	Reaction Type
30	Reference
9	Source Tissue
28	Specific Activity [micromol/min/mg]
2	Storage Stability
82	Substrates and Products (Substrate)
6	Subunits
80	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Temperature Stability [°C]
11	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.2.1.22 - lactaldehyde dehydrogenase

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Ca2+

Cu2+

glyceraldehyde

substrate inhibition

glycolaldehyde

substrate inhibition

Hg2+

Saccharomyces cerevisiae

288132

iodacetamide

Methanocaldococcus jannaschii

iodoacetate

lactaldehyde

substrate inhibition

methylglyoxal

substrate inhibition

Mg2+

Mn2+

50% inhibition at 10 mM

288133

N-ethylmaleimide

2 entries

Ni2+

Saccharomyces cerevisiae

288132

p-chloromercuribenzoate

Saccharomyces cerevisiae

288132

p-hydroxymercuribenzoate

Escherichia coli

50% inhibition at 1.5 mM

288133

Zn2+

Escherichia coli

50% inhibition at 0.4 mM

288133

additional information

Saccharomyces cerevisiae

iodoacetamide, Mn2+, Mg2+, Co2+, no effect at 5 mM

288132