1.2.1.11: aspartate-semialdehyde dehydrogenase

This is an abbreviated version!
For detailed information about aspartate-semialdehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.11

1.2.1.11

diaminopimelate

aspartokinase

dihydrodipicolinate

balanced-lethal

beta-aspartyl

drug development

medicine

biotechnology

pharmacology

synthesis

Reaction

Synonyms

AFUA_3G06830, ASA dehydrogenase, ASA DH, ASA-DH, ASADH, ASADHD, Asd, ASD enzyme, Asd1, Asd2, AsdA, aspartate beta-semialdehyde dehydrogenase, aspartate semialdehyde dehydrogenase, aspartate-beta-semialdehyde dehydrogenase, aspartate-beta-semialdeyhyde dehydrogenase, aspartate-semialdehyde dehydrogenase, aspartic acid semialdehyde dehydrogenase, aspartic beta-semialdehyde dehydrogenase, aspartic semialdehyde dehydrogenase, aspartyl beta-semialdehyde dehydrogenase, aspartyl semialdehyde dehydrogenase, BDCG_01946, CNA02450, dehydrogenase, aspartate semialdehyde, ecASADH, FtASADH, hiASADH, L-aspartate-beta-semialdehyde dehydrogenase, L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosphorylating), Rv3708c

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.11 aspartate-semialdehyde dehydrogenase

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Results	in table
1	Activating Compound
43006	AA Sequence
20	Application
1	CAS Registry Number
37	Cloned(Commentary)
96	Cofactor
20	Crystallization (Commentary)
43	General Information
3	General Stability
1	IC50 Value
213	Inhibitors
8	kcat/KM [mM/s]
118	Ki Value [mM]
69	KM Value [mM]
22	Molecular Weight [Da]
74	Natural Substrates/ Products (Substrates)
306	Organism
23	Pathway
104	PDB ID
19	pH Optimum
2	pH Range
25	Protein Variants
35	Purification (Commentary)
7	Reaction
12	Reaction Type
90	Reference
5	Source Tissue
37	Specific Activity [micromol/min/mg]
6	Storage Stability
137	Substrates and Products (Substrate)
46	Subunits
145	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
4	Temperature Stability [°C]
26	Turnover Number [1/s]

KM Value

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KM Value on EC 1.2.1.11 - aspartate-semialdehyde dehydrogenase

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1.6

arsenate

Escherichia coli

390200

140

cacodylate

Haemophilus influenzae

P44801

recombinant wild-type enzyme, pH 9.0, 30°C

654110

HAsO42-

Escherichia coli

390180

0.16

L-4-aspartyl phosphate

2 entries

0.12 - 2.6

L-aspartate 4-semialdehyde

8 entries

0.03 - 0.955

L-aspartate-4-semialdehyde

7 entries

1.7 - 11.4

NAD+

4 entries

0.0026 - 1.6

NADP+

20 entries

0.02 - 3.3

NADPH

5 entries

0.032 - 240

phosphate

17 entries

0.14

vanadate

Escherichia coli

390200