Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.19.6.1: nitrogenase (flavodoxin)

This is an abbreviated version!
For detailed information about nitrogenase (flavodoxin), go to the full flat file.

Word Map on EC 1.19.6.1

Reaction

4 reduced flavodoxin + 2 H+ +

N2
+ 16 ATP + 16 H2O = 4 oxidized flavodoxin + 2 NH4+ +
H2
+ 16 ADP + 16 phosphate

Synonyms

FeP, FldA, NifF, nitrogenase, nitrogenase Fe protein, nitrogenase Fe-protein

ECTree

     1 Oxidoreductases
         1.19 Acting on reduced flavodoxin as donor
             1.19.6 With dinitrogen as acceptor
                1.19.6.1 nitrogenase (flavodoxin)

Inhibitors

Inhibitors on EC 1.19.6.1 - nitrogenase (flavodoxin)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
diazene
-
inhibits proton reduction
H2
-
inhibits both N2 and diazene reduction
NIFI1,2
-
a regulatory protein, inhibits nitrogenase by competing with Fe protein for binding to the MoFe protein, NifI1,2 inhibits ATP- and MoFe protein-dependent oxidation of the Fe protein, and NIFI1,2 binding prevents association of the two nitrogenase components, the inhibition is relieved by 2-oxoglutarate. NIFI1,2 is unable to bind to an AlF4- stabilized Fe protein:MoFe protein complex. Both nifI1 and nifI2 are required for regulation in vivo
-
nitrate
-
2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide suppresses the inhibition by nitrate
O2
-
complete reversible inhibition, reversibility decreases by increasing the time of exposure to O2
sodium nitroprusside
-
inhibits acetylene-reduction activity of nitrogenase by 1 mM