1.18.1.6: adrenodoxin-NADP+ reductase

This is an abbreviated version!
For detailed information about adrenodoxin-NADP+ reductase, go to the full flat file.

Reaction

2 reduced adrenodoxin +

Synonyms

AdR, adrenodoxin oxidoreductase, adrenodoxin reductase, ADX reductase, AdxR, FDXR, ferredoxin reductase, FLP, FprA, NADPH adrenodoxin reductase, NADPH-adrenodoxin reductase, NADPH-dependent adrenodoxin reductase, NADPH:adrenal ferredoxin adrenodoxin reductase, NADPH:adrenal ferredoxin oxidoreductase, NADPH:adrenodoxin oxidoreductase, NADPH:adrenodoxin oxidoreductase mitochondrial, NADPH:adrenodoxin reductase, nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase, TPNH-cytochrome P-450 reductase

ECTree

     1 Oxidoreductases

         1.18 Acting on iron-sulfur proteins as donors

             1.18.1 With NAD⁺ or NADP⁺ as acceptor

                1.18.1.6 adrenodoxin-NADP+ reductase

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Results	in table
1	Activating Compound
3304	AA Sequence
7	Cloned(Commentary)
37	Cofactor
7	Crystallization (Commentary)
41	Disease/ Diagnostics
2	Expression
5	General Information
4	Inhibitors
1	Ki Value [mM]
11	KM Value [mM]
24	Localization
18	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
40	Organism
2	Pathway
3	PDB ID
1	pH Optimum
10	Purification (Commentary)
1	Reaction
40	Reference
29	Source Tissue
11	Specific Activity [micromol/min/mg]
1	Storage Stability
45	Substrates and Products (Substrate)
10	Subunits
72	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
4	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.18.1.6 - adrenodoxin-NADP+ reductase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

NADPH + oxidized ferredoxin

NADP+ + reduced ferredoxin

2 entries

oxidized adrenodoxin + NADPH + H+

reduced adrenodoxin + NADP+

Bos taurus

-

-

718957, 719389

-

-

?

reduced adrenodoxin + NADP+ + H+

oxidized adrenodoxin + NADPH

3 entries

reduced ferredoxin + NAD(P)+

oxidized ferredoxin + NAD(P)H

Mycobacterium tuberculosis

P9WIQ3

-

657824

-

-

r

NADPH + oxidized ferredoxin

NADP+ + reduced ferredoxin

Bos taurus

-

first enzyme in mitochondrial P-450-linked monooxygenase system catalyzing several steps in the biosynthesis of steroid hormones, bile acids or vitamin D3 in various tissues

285476

-

-

?

NADPH + oxidized ferredoxin

NADP+ + reduced ferredoxin

Sus scrofa

-

first enzyme in mitochondrial P-450-linked monooxygenase system catalyzing several steps in the biosynthesis of steroid hormones, bile acids or vitamin D3 in various tissues

285477

-

-

?

reduced adrenodoxin + NADP+ + H+

oxidized adrenodoxin + NADPH

Bos taurus

-

-

744908, 744909, 745425, 746501

-

-

?

reduced adrenodoxin + NADP+ + H+

oxidized adrenodoxin + NADPH

Bos taurus

P08165

-

745575

-

-

?

reduced adrenodoxin + NADP+ + H+

oxidized adrenodoxin + NADPH

Homo sapiens

-

-

744400, 746398

-

-

?