1.18.1.6: adrenodoxin-NADP+ reductase
This is an abbreviated version!
For detailed information about adrenodoxin-NADP+ reductase, go to the full flat file.
Word Map on EC 1.18.1.6
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1.18.1.6
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dioxygenase
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carbazole
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1,9a-dioxygenase
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25-hydroxyvitamin
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cardo
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rieske
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p450scc
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cyp11a1
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rieske-type
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26-hydroxylation
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alpha-triol
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putidaredoxin
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beta-cholestane-3
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ring-hydroxylating
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meta-cleavage
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novosphingobium
- 1.18.1.6
- dioxygenase
- carbazole
-
1,9a-dioxygenase
-
25-hydroxyvitamin
- cardo
-
rieske
- p450scc
- cyp11a1
-
rieske-type
-
26-hydroxylation
-
alpha-triol
- putidaredoxin
-
beta-cholestane-3
-
ring-hydroxylating
-
meta-cleavage
- novosphingobium
Reaction
2 reduced adrenodoxin + + = 2 oxidized adrenodoxin +
Synonyms
AdR, adrenodoxin oxidoreductase, adrenodoxin reductase, ADX reductase, AdxR, FDXR, ferredoxin reductase, FLP, FprA, NADPH adrenodoxin reductase, NADPH-adrenodoxin reductase, NADPH-dependent adrenodoxin reductase, NADPH:adrenal ferredoxin adrenodoxin reductase, NADPH:adrenal ferredoxin oxidoreductase, NADPH:adrenodoxin oxidoreductase, NADPH:adrenodoxin oxidoreductase mitochondrial, NADPH:adrenodoxin reductase, nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase, TPNH-cytochrome P-450 reductase
ECTree
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Disease
Disease on EC 1.18.1.6 - adrenodoxin-NADP+ reductase
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Carcinoma
Ferredoxin Reductase Is Useful for Predicting the Effect of Chemoradiation Therapy on Esophageal Squamous Cell Carcinoma.
Colorectal Neoplasms
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells.
Colorectal Neoplasms
Ferredoxin reductase: pharmacogenomic assessment in colorectal cancer.
Colorectal Neoplasms
Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin.
Colorectal Neoplasms
Influence of 5-fluorouracil on ferredoxin reductase mRNA splice variants in colorectal carcinomas.
Esophageal Squamous Cell Carcinoma
Ferredoxin Reductase Is Useful for Predicting the Effect of Chemoradiation Therapy on Esophageal Squamous Cell Carcinoma.
Hearing Loss
Report of a case with ferredoxin reductase (FDXR) gene variants in a Chinese boy exhibiting hearing loss, visual impairment, and motor retardation.
Herpes Zoster
Localization of cytochrome P-450-linked mixed function oxidase and steroid hydroxylations within zones of bovine adrenocortices.
Herpes Zoster
Zonal distribution of cytochromes P-450 and related enzymes of bovine adrenal cortex--quantitative assay of concentrations and total contents.
Iron Overload
Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis.
Neoplasms
Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2.
Neoplasms
Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.
Neoplasms
Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.
Neoplasms
Ferredoxin reductase regulates proliferation, differentiation, cell cycle and lipogenesis but not apoptosis in SZ95 sebocytes.
Neoplasms
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
Optic Atrophy
Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy.
Vision Disorders
Report of a case with ferredoxin reductase (FDXR) gene variants in a Chinese boy exhibiting hearing loss, visual impairment, and motor retardation.
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