1.18.1.2: ferredoxin-NADP+ reductase
This is an abbreviated version!
For detailed information about ferredoxin-NADP+ reductase, go to the full flat file.
Word Map on EC 1.18.1.2
-
1.18.1.2
-
nitrate
-
ferredoxins
-
denitrification
-
denitrify
-
reductases
-
heme
-
fad
-
spinach
-
chloroplast
-
copper
-
ammonia
-
nitrous
-
flavin
-
dissimilatory
-
photosystems
-
flavodoxins
-
denitrificans
-
alcaligenes
-
paracoccus
-
n2o
-
anabaena
-
copper-containing
-
thylakoids
-
anammox
-
p450scc
-
semiquinone
-
diaphorase
-
viologen
-
azurins
-
ferredoxin-dependent
-
stutzeri
-
plant-type
-
achromobacter
-
flavoenzymes
-
electron-transfer
-
ammonia-oxidizing
-
plastocyanin
-
dinitrogen
-
photoreduction
-
gogat
-
pregnenolone
-
nitrate-induced
-
xylosoxidans
-
photoreduced
-
wolinella
-
isoalloxazine
-
nitrate-reducing
-
biotechnology
-
nitrosomonas
-
deoxyhemoglobin
-
agriculture
-
single-electron
- 1.18.1.2
- nitrate
- ferredoxins
-
denitrification
-
denitrify
- reductases
- heme
- fad
- spinach
- chloroplast
- copper
- ammonia
-
nitrous
- flavin
-
dissimilatory
- photosystems
- flavodoxins
- denitrificans
- alcaligenes
- paracoccus
- n2o
- anabaena
-
copper-containing
- thylakoids
-
anammox
- p450scc
- semiquinone
- diaphorase
- viologen
- azurins
-
ferredoxin-dependent
- stutzeri
-
plant-type
- achromobacter
-
flavoenzymes
-
electron-transfer
-
ammonia-oxidizing
- plastocyanin
-
dinitrogen
-
photoreduction
- gogat
- pregnenolone
-
nitrate-induced
- xylosoxidans
-
photoreduced
-
wolinella
- isoalloxazine
-
nitrate-reducing
- biotechnology
- nitrosomonas
-
deoxyhemoglobin
- agriculture
-
single-electron
Reaction
2 reduced ferredoxin
+
Synonyms
ABO_0145, adrenodoxin reductase, AnFNR, BsFNR, CT1512, cytochrome b6f -associated ferredoxin:NADP+ oxidoreductase, DA1, EC 1.6.7.1, EC 1.6.99.4, Fd-NADP+ reductase, ferredoxin (flavodoxin)-(reduced) nicotinamide adenine dinucleotide phosphate reductase, ferredoxin (flavodoxin)-NAD(P)H reductase, ferredoxin (flavodoxin)-NADP(H) reductase, ferredoxin (flavodoxin):NADP+ oxidoreductase, ferredoxin NADP oxidoreductase, ferredoxin NADP reductase, ferredoxin NADP(H) oxidoreductase, ferredoxin NADP+ oxidoreductase, ferredoxin NADP+ reductase, ferredoxin nicotinamide adenine dinucleotide phosphate reductase, ferredoxin-NAD(P)+ oxidoreductase, ferredoxin-NAD(P)+ reductase, ferredoxin-NAD(P)H reductase, ferredoxin-NADP oxidoreductase, ferredoxin-NADP reductase, Ferredoxin-NADP(+) reductase, ferredoxin-NADP(H) oxidoreductase, ferredoxin-NADP(H) reductase, ferredoxin-NADP+ oxidoreductase, ferredoxin-NADP+ reductase, ferredoxin-NADP+-oxidoreductase, ferredoxin-NADP+-reductase, ferredoxin-NADP-oxidoreductase, ferredoxin-NADP-reductase, ferredoxin-nicotinamide adenine dinucleotide phosphate reductase, ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase, ferredoxin-TPN reductase, ferredoxin: NADP(+) oxidoreductase, ferredoxin: NADP+ oxidoreductase, ferredoxin:NADP oxidoreductase, ferredoxin:NADP(+) oxidoreductase, ferredoxin:NADP(H) oxidoreductase, ferredoxin:NADP(H) oxidoreductase 2, ferredoxin:NADP+ oxidoreductase, ferredoxin:NADP+ reductase, ferredoxin:NADPH oxidoreductase, ferric reductase, Flavodoxin reductase, FLDR, FLXR, FNR, FNR-A, FNR-B, FNR1, FNR2, FNRII, FNRL, FNRS, FPR, FprA, FprB, Fprs, LFNR1, LFNR2, mitochondrial-type ferredoxin:NADP+ reductase, More, mtFNR, NADH-dependent reduced ferredoxin:NADP oxidoreductase, NADP:ferredoxin oxidoreductase, NADPH ferredoxin reductase, NADPH-dependent ferredoxin reductase, NADPH:ferredoxin oxidoreductase, NfnAB, NfnIII, NFR, PETH, PfFNR, pFNR, photosynthetic ferredoxin NADP+ oxidoreductase, photosynthetic FNR, plastidic-type ferredoxin-NADP+ reductase, PP4_41290, RcFPR, reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase, reductase, ferredoxin-nicotinamide adenine dinucleotide phosphate, RFNR2, ST2133, TgFNR, TPNH-ferredoxin reductase, YumC
ECTree
1.18.1.2 ferredoxin-NADP+ reductaseAdvanced search results
results (
results (KCat KM Value
KCat KM Value on EC 1.18.1.2 - ferredoxin-NADP+ reductase
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kcat/KM VALUE [1/mMs-1] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
8.9
1,4-dioxo-2-(trifluoromethyl)-1lambda5,4lambda5-quinoxaline
pH 7.4, 25°C
-
38
1,4-dioxo-7-(trifluoromethoxy)-1lambda5,2,4lambda5-benzotriazin-3-amine
pH 7.4, 25°C
-
18
3-amino-1,4-dioxo-1lambda5,4lambda5-quinoxaline-2-carbonitrile
pH 7.4, 25°C
-
8000
Ferredoxin
Plasmodium falciparum ferredoxin PfFd is tested;using cytochrome c as electron acceptor
-
48
methyl (1,4-dioxo-1lambda5,2,4lambda5-benzotriazin-3-yl)carbamate
pH 7.4, 25°C
-
26
N-(1,4-dioxo-1lambda5,2,4lambda5-benzotriazin-3-yl)-1,1,1-trifluoromethanesulfonamide
pH 7.4, 25°C
-
62
N-(1,4-dioxo-1lambda5,2,4lambda5-benzotriazin-3-yl)acetamide
pH 7.4, 25°C
-
7.9
N-(1,4-dioxo-1lambda5,2,4lambda5-benzotriazin-3-yl)methanesulfonamide
pH 7.4, 25°C
-
1.6
N-(1-oxo-1lambda5,2,4-benzotriazin-3-yl)acetamide
pH 7.4, 25°C
-
76.3
Fe(III)-EDTA
in the presence of 0.15 mM Fe(III)-EDTA, in the absence of free flavin, in 50 mM sodium phosphate (pH 7.0), at 25°C
972
Fe(III)-EDTA
in the presence of 0.15 mM Fe(III)-EDTA, in the presence of 0.15 mM FAD, in 50 mM sodium phosphate (pH 7.0), at 25°C
3700
ferricytochrome c
-
mutant bearing a truncated N-terminal domain beginning after the KISKK domain, pH 7.5, temperature not specified in the publication
4520
ferricytochrome c
-
mutant bearing lysine to glutamine mutations in the second and third lysine residues of the KISKK domain, pH 7.5, temperature not specified in the publication
12640
ferricytochrome c
-
mutant with an extended N-terminal region to include the EAxxPA motif of maize, pH 7.5, temperature not specified in the publication
12830
ferricytochrome c
-
mutant bearing an N-terminal region with the full wheat KISKK domain, pH 7.5, temperature not specified in the publication
18940
ferricytochrome c
-
mutant bearing a lysine to glutamine mutation in the second lysine residue of the KISKK domain, pH 7.5, temperature not specified in the publication
31710
ferricytochrome c
-
mutant bearing a lysine to glutamine mutation in the first lysine residue of the KISKK domain, pH 7.5, temperature not specified in the publication
33330
ferricytochrome c
-
wild-type, pH 7.5, temperature not specified in the publication
350
flavodoxin
-
using cytochrome c as electron acceptor, for mutant I59E/I92E
-
450
flavodoxin
-
using cytochrome c as electron acceptor, for mutant I59A/I92A
-
0.0004
NADH
mutant T155G/A160T/S223D/Y235F/L263P/R264P/G265P, called AMP2PP5
0.8
NADH
mutant with additional tryptophan residue at the C-terminus, pH 8.0, 30°C
15
NADH
mutant with an insertion of the iloop of Pisum sativum enzyme plus deletion of residue W248, pH 8.0, 30°C
30
NADH
-
for FprA in a flavin free assay, using Fe(III)-citrate as electron acceptor
70
NADH
-
for FprA in a cytochrome c assay, using Pseudomonas putida [4Fe-4S]-ferredoxin FdxA as electron acceptor
90
NADH
-
for FprA in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdA as electron acceptor
90
NADH
-
for FprA in a flavin free assay, using 2,6-dichlorophenolindophenol as electron acceptor
110
NADH
-
for FprA in a flavin free assay, using Fe(III)-EDTA as electron acceptor
110
NADH
-
for FprA in a flavin free assay, using K3Fe(CN)6 as electron acceptor
130
NADH
-
for FprA in a cytochrome c assay, using Pseudomonas putida flavodoxin Fld as electron acceptor
170
NADH
-
for FprA in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdB as electron acceptor
540
NADH
-
for FprB in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdB as electron acceptor
550
NADH
-
for FprA with FAD as cofactor, using Fe(III)-EDTA as electron acceptor
680
NADH
-
for FprB in a flavin free assay, using 2,6-dichlorophenolindophenol as electron acceptor
860
NADH
-
for FprB in a flavin free assay, using K3Fe(CN)6 as electron acceptor
930
NADH
-
for FprA with FAD as cofactor, using Fe(III)-citrate as electron acceptor
1060
NADH
-
for FprA with FMN as cofactor, using Fe(III)-EDTA as electron acceptor
1060
NADH
-
for FprB with FAD as cofactor, using Fe(III)-EDTA as electron acceptor
1170
NADH
-
for FprB in a flavin free assay, using Fe(III)-EDTA as electron acceptor
1860
NADH
-
for FprB in a cytochrome c assay, using Pseudomonas putida flavodoxin Fld as electron acceptor
2690
NADH
-
for FprB with FMN as cofactor, using Fe(III)-EDTA as electron acceptor
2870
NADH
-
for FprA with FMN as cofactor, using Fe(III)-citrate as electron acceptor
3130
NADH
-
for FprB with FAD as cofactor, using Fe(III)-citrate as electron acceptor
3270
NADH
-
for FprB in a flavin free assay, using Fe(III)-citrate as electron acceptor
4630
NADH
-
for FprB in a cytochrome c assay, using Pseudomonas putida [4Fe-4S]-ferredoxin FdxA as electron acceptor
6730
NADH
-
for FprB in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdA as electron acceptor
7090
NADH
-
for FprB with FMN as cofactor, using Fe(III)-citrate as electron acceptor
20
NADPH
in an assay using K3Fe(CN)6 as electron acceptor for mutant H286L
45
NADPH
in an assay using 2,6-dichlorophenolindophenol as electron acceptor for mutant H286K
49
NADPH
in an assay using 2,6-dichlorophenolindophenol as electron acceptor for mutant H286A
85
NADPH
in an assay using K3Fe(CN)6 as electron acceptor for mutant H286A
90
NADPH
-
for FprB in a flavin free assay, using Fe(III)-EDTA as electron acceptor
530
NADPH
-
for FprA in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdB as electron acceptor
720
NADPH
-
for FprB with FAD as cofactor, using Fe(III)-EDTA as electron acceptor
750
NADPH
in an assay using 2,6-dichlorophenolindophenol as electron acceptor
770
NADPH
-
for FprB in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdB as electron acceptor
770
NADPH
-
for FprB with FMN as cofactor, using Fe(III)-EDTA as electron acceptor
840
NADPH
-
for FprA with FAD as cofactor, using Fe(III)-EDTA as electron acceptor
930
NADPH
-
for FprB with FAD as cofactor, using Fe(III)-citrate as electron acceptor
1000
NADPH
-
for FprA in a flavin free assay, using 2,6-dichlorophenolindophenol as electron acceptor
1130
NADPH
-
for FprB in a flavin free assay, using K3Fe(CN)6 as electron acceptor
1140
NADPH
-
for FprB in a flavin free assay, using 2,6-dichlorophenolindophenol as electron acceptor
1190
NADPH
-
for FprA with FAD as cofactor, using Fe(III)-citrate as electron acceptor
1300
NADPH
using 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride as electron acceptor
1320
NADPH
-
for FprA in a flavin free assay, using Fe(III)-EDTA as electron acceptor
1370
NADPH
-
for FprA in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdA as electron acceptor
1570
NADPH
-
for FprA in a flavin free assay, using Fe(III)-citrate as electron acceptor
1680
NADPH
-
for FprA with FMN as cofactor, using Fe(III)-EDTA as electron acceptor
1700
NADPH
mutant with additional tryptophan residue at the C-terminus, pH 8.0, 30°C
2000
NADPH
with 2,6-dichlorophenolindophenol as cosubstrate, at pH 7.0 and 25°C
2090
NADPH
-
for FprB in a flavin free assay, using Fe(III)-citrate as electron acceptor
3050
NADPH
-
for FprA in a cytochrome c assay, using Pseudomonas putida [4Fe-4S]-ferredoxin FdxA as electron acceptor
3150
NADPH
in an assay using 2,6-dichlorophenolindophenol as electron acceptor for mutant H286Q
3230
NADPH
-
for FprA in a flavin free assay, using K3Fe(CN)6 as electron acceptor
3300
NADPH
in an assay using K3Fe(CN)6 as electron acceptor for mutant H286Q
3400
NADPH
-
enzyme in soluble extract, with oxidized 2,6-dichlorophenolindophenol as cosubstrate, at pH 8.0, temperature not specified in the publication
3720
NADPH
-
for FprB in a cytochrome c assay, using Pseudomonas putida flavodoxin Fld as electron acceptor
4590
NADPH
-
for FprB in a cytochrome c assay, using Pseudomonas putida [4Fe-4S]-ferredoxin FdxA as electron acceptor
6040
NADPH
-
for FprA with FMN as cofactor, using Fe(III)-citrate as electron acceptor
6800
NADPH
mutant with an insertion of the iloop of Pisum sativum enzyme, pH 8.0, 30°C
6900
NADPH
-
enzyme in PBS, with oxidized 2,6-dichlorophenolindophenol as cosubstrate, at pH 8.0, temperature not specified in the publication
11000
NADPH
-
for FprB in a cytochrome c assay, using Pseudomonas putida [2Fe-2S]-ferredoxin FdA as electron acceptor
11300
NADPH
pH 8.0, temperature not specified in the publication
11510
NADPH
-
for FprA in a cytochrome c assay, using Pseudomonas putida flavodoxin Fld as electron acceptor
15000
NADPH
-
with 2 mM ferricyanide in 20 mM HEPES-NaOH buffer, at pH 7.0 and 25°C
17000
NADPH
-
for FprB with FMN as cofactor, using Fe(III)-citrate as electron acceptor
33000
NADPH
mutant with an insertion of the iloop of Pisum sativum enzyme plus deletion of residue W248, pH 8.0, 30°C
500
oxidized ferredoxin
mutant with an insertion of the iloop of Pisum sativum enzyme plus deletion of residue W248, pH 8.0, 30°C
10700
oxidized ferredoxin
mutant with an insertion of the iloop of Pisum sativum enzyme, pH 8.0, 30°C
39800
oxidized ferredoxin
mutant with additional tryptophan residue at the C-terminus, pH 8.0, 30°C
