1.18.1.1: rubredoxin-NAD+ reductase
This is an abbreviated version!
For detailed information about rubredoxin-NAD+ reductase, go to the full flat file.
Reaction
Synonyms
(flavo)rubredoxin reductase, ABO_0162, dihydronicotinamide adenine dinucleotide-rubredoxin reductase, DPNH-rubredoxin reductase, EC 1.6.7.2, FIRd-reductase, NAD(P)H:rubredoxin reductase, NADH-rubredoxin oxidoreductase, NADH-rubredoxin reductase, NADH: rubredoxin oxidoreductase, NADH:rubredoxin oxidoreductase, NOR, NROR, RdxR, reduced nicotinamide adenine dinucleotide-rubredoxin reductase, reductase, rubredoxin-nicotinamide adenine dinucleotide, rubB, rubredoxin reductase, rubredoxin-NAD reductase
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Natural Substrates Products on EC 1.18.1.1 - rubredoxin-NAD+ reductase
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REACTION DIAGRAM
reduced rubredoxin + NAD(P)+
oxidized rubredoxin + NAD(P)H
the enzyme and two rubredoxins form a system indipensable for metabolizing n-alkanes, they constitute an electron transport pathway that shuttles reducing equivalents from carbon metabolism to the membrane-bound alkane hydroxylases AlkB1 and AlkB2
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NAD+ + reduced rubredoxin
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the induction of rubredoxin reductase, normally observed at pH 4.3 is stopped immediately after the addition of rifampicin. The enzyme could play a role in some deacidification mechanism in relation to proton transport
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NADH + oxidized rubredoxin
NAD+ + reduced rubredoxin
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enzyme is required for fatty acid and alkane hydroxylation
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