1.17.99.6: epoxyqueuosine reductase
This is an abbreviated version!
For detailed information about epoxyqueuosine reductase, go to the full flat file.
Word Map on EC 1.17.99.6
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1.17.99.6
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wobble
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asp
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hypermodified
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tyr
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cobalt
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dehalogenase
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carbon-halogen
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thermophilus
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base-off
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cobalamin-dependent
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salvage
- 1.17.99.6
-
wobble
- asp
-
hypermodified
- tyr
- cobalt
-
dehalogenase
-
carbon-halogen
- thermophilus
-
base-off
-
cobalamin-dependent
-
salvage
Reaction
Synonyms
duf 208, oQ reductase, QueG, queH
ECTree
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Systematic Name
Systematic Name on EC 1.17.99.6 - epoxyqueuosine reductase
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queuosine34 in tRNA:acceptor oxidoreductase
This enzyme catalyses the last step in the bacterial biosynthetic pathway to queuosine, the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn. Two types of enzymes are known to catalyse this activity. QueG enzymes are cobalamin-dependent, while QueH enzymes contain a [4Fe-4S] metallocluster along with an adjacent coordinated iron metal.