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1.17.99.3: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase

This is an abbreviated version!
For detailed information about 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase, go to the full flat file.

Reaction

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA
+
H2O
+
acceptor
=
(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA
+
reduced acceptor

Synonyms

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase, 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase, alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase, THC-CoA oxidase, THCA-CoA oxidase, THCCox, Trihydroxycoprostanoyl-CoA oxidase

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.99 With unknown physiological acceptors
                1.17.99.3 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase

General Stability

General Stability on EC 1.17.99.3 - 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
in presence of dithiothreitol, the enzyme is very stable in high concentrations of ethylene glycol,1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 2,3-butanediol and 1,3-butanediol, 40-60 v/v
-