1.17.7.4: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

This is an abbreviated version!
For detailed information about 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, go to the full flat file.

Word Map on EC 1.17.7.4

1.17.7.4

isoprenoids

dimethylallyl

4-phosphate

methylerythritol

1-hydroxy-2-methyl-2-e-butenyl

2-c-methyl-d-erythritol

dmapp

1-deoxy-d-xylulose

reductoisomerase

1-deoxy-d-xylulose-5-phosphate

e-4-hydroxy-3-methylbut-2-enyl

isoprene

bertoni

rebaudiana

steviol

methyl-jasmonate

synthesis

Reaction

+ 2 oxidized ferredoxin [iron-sulfur] cluster +

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

+ 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+

Synonyms

(E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate reductase, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1, 4-hydroxy-3-methylbut-2-enyl pyrophosphate reductase, BgHDR1, BgHDR2, chloroplast biogenesis6, Clb6, DsHDR, E-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, EC 1.17.1.2, HDR, HDR1, HMBPP reductase, HsHDR1, HsHDR2, isoprenoid synthesis H, ispH, lysis-tolerant B, LytB, reductase, (E)-4-hydroxy-3-methylbut-2-enyl diphosphate, SrHDR

ECTree

1 Oxidoreductases

1.17 Acting on CH or CH₂ groups

1.17.7 With an iron-sulfur protein as acceptor

1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

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Results	in table
33646	AA Sequence
1	Application
1	CAS Registry Number
16	Cloned(Commentary)
12	Cofactor
2	Crystallization (Commentary)
6	Expression
17	General Information
1	General Stability
4	IC50 Value
26	Inhibitors
2	kcat/KM [mM/s]
4	Ki Value [mM]
4	KM Value [mM]
8	Localization
14	Metals/Ions
8	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
33	Organism
2	Oxidation Stability
7	Pathway
3	pH Optimum
3	pI Value
11	Protein Variants
8	Purification (Commentary)
8	Reaction
3	Reaction Type
32	Reference
1	Renatured (Commentary)
20	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
54	Substrates and Products (Substrate)
9	Subunits
70	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
3	Turnover Number [1/s]

Organism

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Organism on EC 1.17.7.4 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

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UniProt

Uniprot

Dunaliella salina CCAP 19/30

Uniprot

BY-2 cells

no activity in Homo sapiens

716772

Phaeodactylum tricornutum

745190

Phlegmariurus carinatus

746563

I6TT54

UniProt

Plasmodium falciparum

727527

Q9BJX6

UniProt

Salvia miltiorrhiza f. alba

gene HDR

737019

T1RJ09

UniProt

Solanum lycopersicum

induced in correlation with carotinoid production during fruit ripening and, in recombinant Arabidopsis thaliana, in correlation with deetiolation of seedlings

663088

Stevia rebaudiana

727591

Tripterygium wilfordii

UniProt