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1.17.7.4: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

This is an abbreviated version!
For detailed information about 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, go to the full flat file.

Word Map on EC 1.17.7.4

Reaction

dimethylallyl diphosphate
+ 2 oxidized ferredoxin [iron-sulfur] cluster +
H2O
=
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate
 + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+

Synonyms

(E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate reductase, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1, 4-hydroxy-3-methylbut-2-enyl pyrophosphate reductase, BgHDR1, BgHDR2, chloroplast biogenesis6, Clb6, DsHDR, E-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, EC 1.17.1.2, HDR, HDR1, HMBPP reductase, HsHDR1, HsHDR2, isoprenoid synthesis H, ispH, lysis-tolerant B, LytB, reductase, (E)-4-hydroxy-3-methylbut-2-enyl diphosphate, SrHDR

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.7 With an iron-sulfur protein as acceptor
                1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

Metals Ions

Metals Ions on EC 1.17.7.4 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Co2+
-
Co2+ and Mn2+, at 0.5 mM, lower the content of isopentenyl diphosphate in the mixture of both products, isopentenyl diphosphate and dimethylallyl diphosphate
Iron
-
(3FE-4S)+ cluster, 2.6 mol of iron per mol of subunit, wild-type, 0.6 mol per mol of subunit, mutant C12S, 0.9 mol per mol of subunit, mutant C92S, 1.4 mol, mutant C197S
Iron-sulfur cluster
additional information
-
no addition of divalent kations required