1.17.5.2: caffeine dehydrogenase

This is an abbreviated version!
For detailed information about caffeine dehydrogenase, go to the full flat file.

Reaction

Synonyms

caffeine dehydrogenase, Cdh, cdhABC

ECTree

1 Oxidoreductases

1.17 Acting on CH or CH₂ groups

1.17.5 With a quinone or similar compound as acceptor

1.17.5.2 caffeine dehydrogenase

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Results	in table
492	AA Sequence
2	Cofactor
1	KM Value [mM]
7	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
3	Organism
3	Pathway
1	pH Optimum
2	pH Range
1	Reaction
3	Reference
1	Specific Activity [micromol/min/mg]
1	Storage Stability
5	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Temperature Stability [°C]
1	Turnover Number [1/s]

Substrates Products

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of the Enzyme Summary Page.

Substrates Products on EC 1.17.5.2 - caffeine dehydrogenase

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caffeine + ubiquinone + H2O

1,3,7-trimethylurate + ubiquinol

Pseudomonas sp. CBB1

745135

caffeine + ubiquinone-0

trimethyl uric acid + ubiquinol-0

Pseudomonas sp.

preferred electron acceptor

708921

the oxygen atom in trimethyl uric acid is derived exclusively from water

theobromine + ubiquinone-0

? + ubiquinol-0

Pseudomonas sp.

46% of the activity with caffeine

708921

theophylline + ubiquinone-0

? + ubiquinol-0

Pseudomonas sp.

0.6% of the activity with caffeine

708921

additional information

Pseudomonas sp.

enzyme is specific for caffeine and theobromine. No activity with xanthine, 3-methylxanthine, 7-methylxanthine, trimethyl uric acid, and 3,7-dimethyl uric acid

708921