1.17.3.3: 6-hydroxynicotinate dehydrogenase

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For detailed information about 6-hydroxynicotinate dehydrogenase, go to the full flat file.

Reaction

Synonyms

6-HDH, 6-hydroxynicotinate hydroxylase, 6-hydroxynicotinic acid dehydrogenase, 6-hydroxynicotinic acid hydroxylase, dehydrogenase, 6-hydroxynicotinate

ECTree

     1 Oxidoreductases

         1.17 Acting on CH or CH₂ groups

             1.17.3 With oxygen as acceptor

                1.17.3.3 6-hydroxynicotinate dehydrogenase

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Results	in table
1	CAS Registry Number
6	Cofactor
1	General Stability
4	Inhibitors
1	KM Value [mM]
1	Localization
2	Metals/Ions
4	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
4	Organism
2	Pathway
1	pH Optimum
2	Purification (Commentary)
2	Reaction
5	Reaction Type
3	Reference
1	Specific Activity [micromol/min/mg]
13	Substrates and Products (Substrate)
1	Subunits
8	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Inhibitors

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Inhibitors on EC 1.17.3.3 - 6-hydroxynicotinate dehydrogenase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

glycerol

Neobacillus niacini

-

at a final concentration 10% (v/v), inactivates to 30% of the initial activity

644533

KCN

Neobacillus niacini

-

-

644533

Na2S

Neobacillus niacini

-

partially purified 6-HDH, 90% loss of activity

644533

additional information

Neobacillus niacini

-

not inhibited by NaCl

644533

-