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1.17.2.1: nicotinate dehydrogenase (cytochrome)

This is an abbreviated version!
For detailed information about nicotinate dehydrogenase (cytochrome), go to the full flat file.

Reaction

nicotinate
+
a ferricytochrome
+
H2O
=
6-Hydroxynicotinate
+
a ferrocytochrome
+ 2 H+

Synonyms

ndhSL, NicA, NicB

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.2 With a cytochrome as acceptor
                1.17.2.1 nicotinate dehydrogenase (cytochrome)

Substrates Products

Substrates Products on EC 1.17.2.1 - nicotinate dehydrogenase (cytochrome)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3-cyanopyridine + 5-methylphenazinium methyl sulfate + H2O
?
show the reaction diagram
-
4% of the activity with nicotinate
-
-
?
nicotinic acid + 5-methylphenazinium methyl sulfate + H2O
6-hydroxynicotinate + ?
show the reaction diagram
nicotinic acid + 5-methylphenazinium methyl sulfate + H2O
6-hydroxynicotinic acid + ?
show the reaction diagram
-
-
-
-
?
nipecotic acid + 5-methylphenazinium methyl sulfate + H2O
?
show the reaction diagram
-
8% of the activity with nicotinate
-
-
?
picolinic acid + 5-methylphenazinium methyl sulfate + H2O
?
show the reaction diagram
-
7% of the activity with nicotinate
-
-
?
pyrazine-2-carboxylic acid + 5-methylphenazinium methyl sulfate + H2O
?
show the reaction diagram
-
8% of the activity with nicotinate
-
-
?
pyridine-3-carboxyaldehyde + 5-methylphenazinium methyl sulfate + H2O
?
show the reaction diagram
-
5% of the activity with nicotinate
-
-
?
pyridine-3-sulfonic acid + 5-methylphenazinium methyl sulfate + H2O
?
show the reaction diagram
-
4% of the activity with nicotinate
-
-
?