1.17.1.8: 4-hydroxy-tetrahydrodipicolinate reductase

This is an abbreviated version!
For detailed information about 4-hydroxy-tetrahydrodipicolinate reductase, go to the full flat file.

Word Map on EC 1.17.1.8

1.17.1.8

diaminopimelate

glutamicum

meso-diaminopimelate

aspartokinase

imine

dhdps

2,6-pyridinedicarboxylate

medicine

alpha,beta-unsaturated

2'-phosphate

s-2-aminoethyl-l-cysteine

aspartate-semialdehyde

drug development

agriculture

Reaction

(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

Synonyms

AbDHDPR, CRR1, DapB, DHDP reductase, DHDPR, DHPR, dihydrodipicolinate reductase, dihydrodipicolinate reductase-like protein, dihydrodipicolinic acid reductase, EC 1.3.1.26, MRSA-DHDPR, reductase, dihydrodipicolinate

ECTree

1 Oxidoreductases

1.17 Acting on CH or CH₂ groups

1.17.1 With NAD⁺ or NADP⁺ as acceptor

1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase

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Results	in table
8	Activating Compound
36207	AA Sequence
6	Application
1	CAS Registry Number
26	Cloned(Commentary)
65	Cofactor
16	Crystallization (Commentary)
18	General Information
61	Inhibitors
15	Ki Value [mM]
60	KM Value [mM]
3	Localization
31	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
76	Organism
11	Pathway
56	PDB ID
13	pH Optimum
3	pH Range
7	Protein Variants
24	Purification (Commentary)
13	Reaction
3	Reaction Type
59	Reference
3	Source Tissue
16	Specific Activity [micromol/min/mg]
2	Storage Stability
100	Substrates and Products (Substrate)
38	Subunits
71	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
17	Turnover Number [1/s]

KI Value

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KI Value on EC 1.17.1.8 - 4-hydroxy-tetrahydrodipicolinate reductase

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0.032 - 5.5

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

5 entries

0.435

(4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate

Escherichia coli

390620

0.33

2,6-pyridinedicarboxylic acid

Escherichia coli

390624

0.085 - 0.9

dipicolinate

3 entries

5.5 - 15

isophthalic acid

2 entries

0.0051 - 0.0081

NADH

2 entries

NADP+

Escherichia coli

390624