1.17.1.4: xanthine dehydrogenase

This is an abbreviated version!
For detailed information about xanthine dehydrogenase, go to the full flat file.

Reaction

Synonyms

AtXDH1, EC 1.1.1.204, EC 1.2.1.37, IAO1, More, NAD-xanthine dehydrogenase, PaoABC, Retinol dehydrogenase, Rosy locus protein, VvXDH, xanthine dehydrogenase, xanthine dehydrogenase-1, xanthine dehydrogenase-2, xanthine dehydrogenase/oxidase, xanthine oxidoreductase, xanthine-NAD oxidoreductase, xanthine/NAD+ oxidoreductase, xanthine:NAD+ oxidoreductase, XDH, XDH/XO, XDH1, XDH2, XdhC, XOR, YagR, YagS, YagT

ECTree

     1 Oxidoreductases

         1.17 Acting on CH or CH₂ groups

             1.17.1 With NAD⁺ or NADP⁺ as acceptor

                1.17.1.4 xanthine dehydrogenase

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Results	in table
22	Activating Compound
13818	AA Sequence
34	Application
1	CAS Registry Number
36	Cloned(Commentary)
299	Cofactor
22	Crystallization (Commentary)
40	Disease/ Diagnostics
3	Expression
84	General Information
9	General Stability
175	Inhibitors
19	kcat/KM [mM/s]
3	Ki Value [mM]
170	KM Value [mM]
22	Localization
133	Metals/Ions
86	Molecular Weight [Da]
237	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
225	Organism
1	Oxidation Stability
14	Pathway
110	PDB ID
45	pH Optimum
8	pH Range
8	pH Stability
1	pI Value
4	Posttranslational Modification
79	Protein Variants
71	Purification (Commentary)
9	Reaction
3	Reaction Type
205	Reference
2	Renatured (Commentary)
217	Source Tissue
65	Specific Activity [micromol/min/mg]
8	Storage Stability
572	Substrates and Products (Substrate)
66	Subunits
107	Synonyms
1	Systematic Name
32	Temperature Optimum [°C]
1	Temperature Range [°C]
22	Temperature Stability [°C]
55	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.17.1.4 - xanthine dehydrogenase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, 24 h, activity of both xanthine oxidase and xanthine oxidase plus dehydrogenase is lower in liver extracts with the combined presence of adenine and dithiotreitol/phenylmethylsulfonyl fluoride

Rattus norvegicus

-

687214

-20°C, pH 8.6, 3 days

Rattus sp.

-

644599

-70°C, 0.1 M sodium diphosphate, 0.3 mM EDTA, pH 7.5, 1 mM salicylate, 2.5 mM DTT, 3 months

Bos taurus

-

644588

-70°C, 6 months

Gottschalkia purinilytica

-

644577

-80°C, 6 months

Delftia acidovorans

-

644583

1°C, 1 mM DTT in conjunction with 0.1 M ammonium sulfate, 60-70% retaining activity after 8-12 days

Colias eurytheme

-

644607

4°C, 1 week

Pseudomonas putida

-

644593

4°C, 25 mM Tris-boric acid, pH 8.5, 2.5 mM EDTA, 2 mM 2-mercaptoethanol, 0.2 mM sodium molybdate, one year

Triticum aestivum

-

644568