1.16.1.9: ferric-chelate reductase (NADPH)

This is an abbreviated version!
For detailed information about ferric-chelate reductase (NADPH), go to the full flat file.

Reaction

2 Fe(II)-siderophore +

Synonyms

FCR, FCR-LM, FCR-Os, Fe(III)-chelate reductase, ferredoxin-NADP(+) oxidoreductase, ferredoxin-NADP+ oxidoreductase, ferri-siderophore reductase, ferric chelate reductase, ferric reductase, ferric siderophore reductase, ferric-chelate reductase, FNR(S), FNRS, FRO1, FRO2, YqjH

ECTree

     1 Oxidoreductases

         1.16 Oxidizing metal ions

             1.16.1 With NAD⁺ or NADP⁺ as acceptor

                1.16.1.9 ferric-chelate reductase (NADPH)

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Results	in table
1	Activating Compound
642	AA Sequence
8	Cloned(Commentary)
16	Cofactor
1	Crystallization (Commentary)
6	Expression
12	General Information
16	kcat/KM [mM/s]
18	KM Value [mM]
4	Localization
6	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
39	Organism
1	pI Value
3	Protein Variants
5	Purification (Commentary)
1	Reaction
12	Reference
5	Source Tissue
4	Specific Activity [micromol/min/mg]
42	Substrates and Products (Substrate)
8	Subunits
30	Synonyms
1	Systematic Name
4	Turnover Number [1/s]

Expression

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Expression on EC 1.16.1.9 - ferric-chelate reductase (NADPH)

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

addition of Fe2+ decreases yqjH expression starting at 100 nM, with a maximum repression of 4fold occurring at 0.01 mM Fe2+. Addition of CoCl2 concentrations of more than 500 nM also repress yqjH expression by about 50%

2 entries

FRO2 transcript shows abundance under iron deficiency. The addition of 300 mM bathocuproine disulfonic acid further reduces FRO2 transcript abundance in plants grown under high-iron conditions for 3 days

Arabidopsis thaliana

-

723258

the enzyme is expressed at high levels in iron-deficient roots

Pisum sativum

-

723453

YqjI-dependent transcriptional repression is reduced when cells are exposed to elevated nickel levels, resulting in increased expression of yqjH. Upon addition of NiCl2, yqjH expression increases starting at 100 nM NiCl2, with maximum induction by 0.001 mM NiCl2 (42%). Deletion of yqjI leads to constitutive expression levels of yqjH that are 30fold higher than wild type basal expression levels

2 entries

addition of Fe2+ decreases yqjH expression starting at 100 nM, with a maximum repression of 4fold occurring at 0.01 mM Fe2+. Addition of CoCl2 concentrations of more than 500 nM also repress yqjH expression by about 50%

Escherichia coli

-

722534

addition of Fe2+ decreases yqjH expression starting at 100 nM, with a maximum repression of 4fold occurring at 0.01 mM Fe2+. Addition of CoCl2 concentrations of more than 500 nM also repress yqjH expression by about 50%

Escherichia coli MG1655

-

-

YqjI-dependent transcriptional repression is reduced when cells are exposed to elevated nickel levels, resulting in increased expression of yqjH. Upon addition of NiCl2, yqjH expression increases starting at 100 nM NiCl2, with maximum induction by 0.001 mM NiCl2 (42%). Deletion of yqjI leads to constitutive expression levels of yqjH that are 30fold higher than wild type basal expression levels

Escherichia coli

-

722534

YqjI-dependent transcriptional repression is reduced when cells are exposed to elevated nickel levels, resulting in increased expression of yqjH. Upon addition of NiCl2, yqjH expression increases starting at 100 nM NiCl2, with maximum induction by 0.001 mM NiCl2 (42%). Deletion of yqjI leads to constitutive expression levels of yqjH that are 30fold higher than wild type basal expression levels

Escherichia coli MG1655

-

-