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1.14.99.50: gamma-glutamyl hercynylcysteine S-oxide synthase

This is an abbreviated version!
For detailed information about gamma-glutamyl hercynylcysteine S-oxide synthase, go to the full flat file.

Word Map on EC 1.14.99.50

Reaction

hercynine
+
gamma-L-glutamyl-L-cysteine
+
O2
=
gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide
+
H2O

Synonyms

5-histidylcysteine sulfoxide synthase, Cabther_A1318, EgtB, EgtBthermo, hercynine oxygenase, sulfoxide synthase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.50 gamma-glutamyl hercynylcysteine S-oxide synthase

Systematic Name

Systematic Name on EC 1.14.99.50 - gamma-glutamyl hercynylcysteine S-oxide synthase

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SYSTEMATIC NAME
IUBMB Comments
hercynine,gamma-L-glutamyl-L-cysteine:oxygen oxidoreductase [gamma-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide-forming]
Requires Fe2+ for activity. The enzyme, found in bacteria, is specific for both hercynine and gamma-L-glutamyl-L-cysteine. It is part of the biosynthesis pathway of ergothioneine.