1.14.99.48: heme oxygenase (staphylobilin-producing)

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For detailed information about heme oxygenase (staphylobilin-producing), go to the full flat file.

Reaction

Synonyms

haem oxidase, haem oxygenase, heme oxidase, heme oxygenase, heme oxygenase (decyclizing), heme oxygenase (staphylobilin-producing) 1, heme oxygenase (staphylobilin-producing) 2, isdG, isdI

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.99 Miscellaneous

                1.14.99.48 heme oxygenase (staphylobilin-producing)

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Results	in table
1	Activating Compound
254	AA Sequence
3	Cloned(Commentary)
6	Crystallization (Commentary)
14	General Information
2	Inhibitors
4	Localization
1	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
76	Organism
3	Pathway
21	Protein Variants
2	Reaction
34	Reference
1	Renatured (Commentary)
36	Substrates and Products (Substrate)
2	Subunits
26	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.14.99.48 - heme oxygenase (staphylobilin-producing)

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SYSTEMATIC NAME

IUBMB Comments

protoheme,hydrogen-donor:oxygen oxidoreductase (delta/beta-methene-oxidizing, hydroxylating)

This enzyme, which is found in some pathogenic bacteria, is involved in an iron acquisition system that catabolizes the host's hemoglobin. The two enzymes from the bacterium Staphylococcus aureus, encoded by the isdG and isdI genes, produce 67.5 % and 56.2 % delta-staphylobilin, respectively.