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1.14.99.4: progesterone monooxygenase

This is an abbreviated version!
For detailed information about progesterone monooxygenase, go to the full flat file.

Word Map on EC 1.14.99.4

Reaction

progesterone
+
reduced acceptor
+
O2
=
Testosterone acetate
+
acceptor
+
H2O

Synonyms

17alpha-progesterone hydroxylase, 17beta-progesterone hydroxylase, CYP2G1, cytochrome P-450/monooxygenase, FMO, progesterone hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.4 progesterone monooxygenase

Systematic Name

Systematic Name on EC 1.14.99.4 - progesterone monooxygenase

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SYSTEMATIC NAME
IUBMB Comments
progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)
Has a wide specificity. A single enzyme from ascomycete the Neonectria radicicola (EC 1.14.13.54 ketosteroid monooxygenase) catalyses both this reaction and that catalysed by EC 1.14.99.12 androst-4-ene-3,17-dione monooxygenase.