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1.14.99.4: progesterone monooxygenase

This is an abbreviated version!
For detailed information about progesterone monooxygenase, go to the full flat file.

Word Map on EC 1.14.99.4

Reaction

progesterone
+
reduced acceptor
+
O2
=
Testosterone acetate
+
acceptor
+
H2O

Synonyms

17alpha-progesterone hydroxylase, 17beta-progesterone hydroxylase, CYP2G1, cytochrome P-450/monooxygenase, FMO, progesterone hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.4 progesterone monooxygenase

General Stability

General Stability on EC 1.14.99.4 - progesterone monooxygenase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
1 mg/ml albumin stabilizes crude enzyme extract for 1 month when kept frozen
-
10 h dialysis of purified enzyme against 0.01 M Tris buffer, pH 7.5, 0.005 M EDTA, leads to 50% loss of activity
-
EDTA affords some protection, especially for crude extracts
-
preparation is highly unstable
-