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1.14.99.39: ammonia monooxygenase

This is an abbreviated version!
For detailed information about ammonia monooxygenase, go to the full flat file.

Word Map on EC 1.14.99.39

Reaction

NH3
+
a reduced acceptor
 +
O2
=
NH2OH
 +
an acceptor
 +
H2O

Synonyms

ammonia monooxygenase, AMO, AMO-Ne, amoA, AmoB, AmoC3, copper-containing membrane-bound monooxygenase, CuMMO, low-temperature ammonia monooxygenase, Ny_amoB

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.39 ammonia monooxygenase

Expression

Expression on EC 1.14.99.39 - ammonia monooxygenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
cells of Nitrosomonas europaea may be able to support two types of ammonia monooxygenase activity. One of these types appears to provide a base level of enzyme activity which is largely insensitive to changes in the available NH3 concentration. This is the activity which is observed at the start of each incubation and the level to which the cells returned after they underwent an initial stimulation of activity and a subsequent decline. The second type of ammonia monooxygenase can be increased in response to increases in NH3 availability and can be rapidly decreased in response to NH3 limitation. These two differentially regulated forms of enzyme activity could be particularly useful to Nitrosomonas europaea for a rapid response to transient fluctuations in ammonia availability and still allow the organism to maintain a basal level of ammonia monooxygenase activity to generate energy for both cell maintenance and the rapid de novo synthesis of protein once ammonia becomes available
-
heat shock induces expression of amoC3
when Nitrosomonas cells are grown with pyruvate as the electron donor and nitrite as the electron acceptor under anoxic conditions, the amount of ammonia monooxygenase in the cells decreases. After about 2 weeks, ammonia monooxygenase is no longer detectable in the denitrifying cells
-