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1.14.99.38: cholesterol 25-monooxygenase

This is an abbreviated version!
For detailed information about cholesterol 25-monooxygenase, go to the full flat file.

Word Map on EC 1.14.99.38

Reaction

cholesterol
+
reduced acceptor
 +
O2
=
25-hydroxycholesterol
 +
acceptor
 +
H2O

Synonyms

CH25A, CH25H, cholesterol 25-hydroxylase, cholesterol 25-monooxygenase, cholesterol-25-hydroxylase, CYP1A2, CYP27A1, CYP2C9, CYP2D6, CYP3A, Cyp3a11, CYP3A4

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.38 cholesterol 25-monooxygenase

Cloned

Cloned on EC 1.14.99.38 - cholesterol 25-monooxygenase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Huh-7.5.1 cells
expressed in MARC-145 cells
-
expression in COS cells, expression of cholesterol 25-hydroxylase in transfected cells reduces the biosynthesis of cholesterol from acetate and suppresses the cleavage of sterol regulatory element binding protein-1 and -2
gene CH25H, DNA and amino acid sequence deterination and analysis, sequence comparisons, gene structures and tandem locations for the human CH25H and LIPA, EC 3.1.1.13, genes on chromosome 10
-
gene CH25H, overexpression in HEK-293T cells
gene Ch25h, quantitative real-time RT-PCR expression analysis
-
intronless gene CH25H is located on chromosome 1, DNA and amino acid sequence deterination and analysis, sequence comparisons, gene structures and tandem locations for the human CH25H and LIPA, EC 3.1.1.13, genes on chromosome 10
intronless gene CH25H is located on chromosome 10, DNA and amino acid sequence deterination and analysis, sequence comparisons, gene structures and tandem locations for the human CH25H and LIPA, EC 3.1.1.13, genes on chromosome 10
intronless gene CH25H is located on chromosome 19, DNA and amino acid sequence deterination and analysis, sequence comparisons, gene structures and tandem locations for the human CH25H and LIPA, EC 3.1.1.13, genes on chromosome 10
intronless gene CH25H is located on chromosome 26, DNA and amino acid sequence deterination and analysis, sequence comparisons, gene structures and tandem locations for the human CH25H and LIPA, EC 3.1.1.13, genes on chromosome 10
intronless gene CH25H is located on chromosome 6, DNA and amino acid sequence deterination and analysis, sequence comparisons, gene structures and tandem locations for the human CH25H and LIPA, EC 3.1.1.13, genes on chromosome 10
-
intronless gene CH25H is located on chromosome 9, DNA and amino acid sequence deterination and analysis, sequence comparisons, gene structures and tandem locations for the human CH25H and LIPA, EC 3.1.1.13, genes on chromosome 10
recombinant expression in insect cell microsomes via baculovirus transfection
the gene encoding the enzyme is located on chromosome 10