1.14.99.22: ecdysone 20-monooxygenase
This is an abbreviated version!
For detailed information about ecdysone 20-monooxygenase, go to the full flat file.
Word Map on EC 1.14.99.22
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1.14.99.22
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20-hydroxyecdysone
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ecdysteroids
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instar
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molt
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midguts
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manduca
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sexta
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wandering
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malpighian
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halloween
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hornworm
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ecdysteroidogenesis
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shade
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prothoracic
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moulting
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migratoria
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nondiapause
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neverland
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cyp18a1
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larval-pupal
- 1.14.99.22
- 20-hydroxyecdysone
- ecdysteroids
-
instar
-
molt
- midguts
- manduca
- sexta
-
wandering
-
malpighian
-
halloween
- hornworm
-
ecdysteroidogenesis
-
shade
-
prothoracic
-
moulting
- migratoria
-
nondiapause
- neverland
-
cyp18a1
-
larval-pupal
Reaction
Synonyms
alpha-ecdysone C-20 hydroxylase, BmE20OHase, Cyp314A1, E-20-M, E20-M, E20M, E20MO, E20OHase, ecdysone 20-hydroxylase, ecdysone 20-monooxygenase, shade, shd
ECTree
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Inhibitors
Inhibitors on EC 1.14.99.22 - ecdysone 20-monooxygenase
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1H-[1,2,4]oxadizolo[4,3-a]-quinoxalin-1-one
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a guanylate cyclase inhibitor, applied with ecdysone agonist RH-5849 results in 63% reduced E20M activity
6-anilinoquinoline-5,6-quinone
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LY-38583, a guanylate cyclase inhibitor, applied with ecdysone agonist RH-5849 results in 80% reduced E20M activity, addition of guanylate cyclase activator S levels the activity to 78% of control activity
methylene blue
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a guanylate cyclase inhibitor, applied with ecdysone agonist RH-5849 results in 86% reduced E20M activity, reversed by addition of dibutyryl-cGMP/theophylline to 87% of control activity
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isolated from the leaves of Impatiens glandulifera
2-methoxy-1,4-naphthoquinone
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isolated from the leaves of Impatiens glandulifera
2-methoxy-1,4-naphthoquinone
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isolated from the leaves of Impatiens glandulifera
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partially reversible by irradiation with monochromatic light
CO
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partially reversible by irradiation with monochromatic light
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7beta-acetoxy-8,13-epoxy-1alpha,6beta,9alpha-dihydroxylabd-14-en-11-one, adenylate cyclase activator
forskolin
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7beta-acetoxy-8,13-epoxy-1alpha,6beta,9alpha-dihydroxylabd-14-en-11-one, adenylate cyclase activator
Metyrapone
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2-methyl-1,2-di-3'-pyridylpropan-1-one, up to 80% inhibition
additional information
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inhibitory effects of guanylate cyclase inhibitors with RH-5849 in vivo, overview
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additional information
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2-hydroxy-1,4-anthraquinone is essentially without effect on enzyme activity
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additional information
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in pure N2 atmosphere, enzyme activity is 50% inhibited due to missing oxygen
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