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1.14.99.12: androst-4-ene-3,17-dione monooxygenase

This is an abbreviated version!
For detailed information about androst-4-ene-3,17-dione monooxygenase, go to the full flat file.

Word Map on EC 1.14.99.12

Reaction

androstenedione
+
reduced acceptor
+
O2
=
testololactone
+
acceptor
+
H2O

Synonyms

4-androstene-3,17-dione monooxygenase, androst-4-ene-3,17-dione 17-oxidoreductase, androst-4-ene-3,17-dione hydroxylase, androstene-3,17-dione hydroxylase, androstenedione monooxygenase, oxygenase, androstenedione mono-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.12 androst-4-ene-3,17-dione monooxygenase

Natural Substrates Products

Natural Substrates Products on EC 1.14.99.12 - androst-4-ene-3,17-dione monooxygenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
androst-4-ene-3,17-dione + AH2 + O2
3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
show the reaction diagram
-
enzyme levels increase after exposure of rats to di-n-butyl phthalate
-
-
?